The neural integrators of the mammalian saccadic system.

The neural integrators of the mammalian saccadic system.
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哺乳动物扫视系统的神经整合器。

DOI:
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发表时间:
1997
期刊:
Frontiers in Bioscience
影响因子:
--
通讯作者:
A. Moschovakis
A. Moschovakis
中科院分区:
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文献类型:
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作者:
A. Moschovakis

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神经速度-位置积分器将爆发发生器的扫视相关信号转换成它们传达给运动神经元的眼睛位置相关的紧张信号。它们主要局限于三个相互联系的中脑结构:1)Cajal间质核(NIC),2)舌下前置核(NPH),3)前庭核(VN)。在水平和垂直平面中的积分分别由NPH-VN和NIC-VN复合体在很大程度上独立地完成。这些区域中的细胞携带或多或少与扫视相关的强相位信号和与眼睛位置相关的紧张信号。根据放电速率与眼睛位置之间的关系,这些细胞进一步细分为规则或不规则,或多或少敏感,双向或单向调节。本文就其放电模式以及爆发神经元和眼外运动神经元的放电模式作一简要介绍。然后,证据有关的输入输出连接的相关细胞类进行了总结。最后,几个建模尝试模拟神经速度-位置积分器,并根据心理物理,解剖,生理和神经学证据评估其逼真性。
The neural velocity to position integrators transform the saccade related signal of the burst generators into an eye position related tonic signal they convey to motoneurons. They are largely confined to three heavily interconnected midbrain structures: 1) The interstitial nucleus of Cajal (NIC), 2) The nucleus prepositus hypoglossi (NPH), 3) The vestibular nuclei (VN). Integration in the horizontal and vertical planes is accomplished largely independently by the NPH-VN and the NIC-VN complexes, respectively. Cells in these regions carry a more or less intense phasic signal related to saccades and a tonic signal related to eye position. Depending on the relationship between the rate of their discharge and the position of the eyes, these cells have been further subdivided into regular or irregular, more or less sensitive, and bi-directionally or uni-directionally modulated. The present review provides a brief description of their discharge pattern and that of burst neurons and extraocular motoneurons. Then, evidence concerning the input-output connections of relevant cell classes is summarized. Finally, several modelling attempts to simulate the neural velocity-to-position integrators are presented and their verisimilitude is evaluated in the light of psychophysical, anatomical, physiological and neurological evidence.
DOI: 10.1152/jn.1996.76.1.332
发表时间: 1996
期刊: Journal of neurophysiology.
影响因子: --
作者:
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期刊: Science (New York, N.Y.)
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发表时间: 1996
期刊: Journal of neurophysiology.
影响因子: --
作者:
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通讯作者: Highstein,SM
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DOI: 10.1152/jn.1986.55.5.1044
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影响因子: 2.5
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