Patient symptoms and experience following COVID-19: results from a UK-wide survey.
Patient symptoms and experience following COVID-19: results from a UK-wide survey.
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DOI：
10.1136/bmjresp-2021-001075
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发表时间：
2021-11
影响因子：
4.1
通讯作者：
Hopkinson NS
中科院分区：
文献类型：
--
作者：
Buttery S;Philip KEJ;Williams P;Fallas A;West B;Cumella A;Cheung C;Walker S;Quint JK;Polkey MI;Hopkinson NS
调查急性COVID-19（通常称为“长期COVID”）后持续不适的人的经历，包括症状和与医疗保健的相互作用。我们对2020年4月至12月期间通过英国在线COVID-19后支持和信息中心进行的一项调查的回复进行了混合方法分析，该调查是关于人们在急性COVID-19后的经历。3290名受访者，78%为女性，92.1%为白人，中位年龄45-54岁；12.7%曾住院治疗。494例（16.5%）在症状出现后4至8周完成调查，641例（21.4%）在8至12周完成调查，1865例（62.1%）在12周后完成调查。最常报告的持续症状是：呼吸困难（92.1%）、疲劳（83.3%）、肌肉无力或关节僵硬（50.6%）、睡眠障碍（46.2%）、智力问题（45.9%）、情绪变化(包括焦虑和抑郁（43.1%）和咳嗽（42.3%）。症状似乎与急性疾病的严重程度或先前存在的疾病无关。对自由文本回复的分析揭示了三个主题：(1)与COVID-19的生活经历：身体和心理症状不可预测地波动；(2)与医疗机构的互动不令人满意；(3)对未来的影响：患者自身状况、社会和医疗体系，以及研究的必要性。考虑患者的观点和经验将有助于制定服务计划，以解决COVID-19急性期后仍有症状的患者持续存在的问题。
To investigate the experience of people who continue to be unwell after acute COVID-19, often referred to as ‘long COVID’, both in terms of their symptoms and their interactions with healthcare. We conducted a mixed-methods analysis of responses to a survey accessed through a UK online post-COVID-19 support and information hub, between April and December 2020, about people’s experiences after having acute COVID-19. 3290 respondents, 78% female, 92.1% white ethnicity and median age range 45–54 years; 12.7% had been hospitalised. 494(16.5%) completed the survey between 4 and 8 weeks of the onset of their symptoms, 641(21.4%) between 8 and 12 weeks and 1865 (62.1%) >12 weeks after. The ongoing symptoms most frequently reported were: breathing problems (92.1%), fatigue (83.3%), muscle weakness or joint stiffness (50.6%), sleep disturbances (46.2%), problems with mental abilities (45.9%), changes in mood, including anxiety and depression (43.1%) and cough (42.3%). Symptoms did not appear to be related to the severity of the acute illness or to the presence of pre-existing medical conditions. Analysis of free-text responses revealed three main themes: (1) experience of living with COVID-19: physical and psychological symptoms that fluctuate unpredictably; (2) interactions with healthcare that were unsatisfactory; (3) implications for the future: their own condition, society and the healthcare system, and the need for research Consideration of patient perspectives and experiences will assist in the planning of services to address problems persisting in people who remain symptomatic after the acute phase of COVID-19.
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COVID-19 的 50 多种长期影响：系统回顾和荟萃分析。
影响因子：
4.6
作者：
Lopez-Leon S;Wegman-Ostrosky T;Perelman C;Sepulveda R;Rebolledo PA;Cuapio A;Villapol S
通讯作者：
Villapol S
DOI：
10.1016/s2213-2600(21)00013-8
发表时间：
2021-07
期刊：
The Lancet. Respiratory medicine
影响因子：
--
作者：
Bloom CI;Drake TM;Docherty AB;Lipworth BJ;Johnston SL;Nguyen-Van-Tam JS;Carson G;Dunning J;Harrison EM;Baillie JK;Semple MG;Cullinan P;Openshaw PJM;ISARIC investigators
通讯作者：
ISARIC investigators
DOI：
10.3390/ph11040113
发表时间：
2018-10-22
期刊：
Pharmaceuticals (Basel, Switzerland)
影响因子：
--
作者：
Rockfield S;Chhabra R;Robertson M;Rehman N;Bisht R;Nanjundan M
通讯作者：
Nanjundan M
影响因子：
10
作者：
Hopkinson, Nicholas S.;Rossi, Niccolo;Falchi, Mario
通讯作者：
Falchi, Mario
影响因子：
2.8
作者：
Ladds E;Rushforth A;Wieringa S;Taylor S;Rayner C;Husain L;Greenhalgh T
通讯作者：
Greenhalgh T