Prefrontal structural and functional brain imaging findings in antisocial, violent, and psychopathic individuals: a meta-analysis.
Prefrontal structural and functional brain imaging findings in antisocial, violent, and psychopathic individuals: a meta-analysis.
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DOI：
10.1016/j.pscychresns.2009.03.012
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发表时间：
2009-11-30
影响因子：
2.3
通讯作者：
Raine, Adrian
中科院分区：
文献类型：
--
作者：
Yang, Yaling;Raine, Adrian
Brain imaging studies suggest that antisocial and violent behavior is associated with structural and functional deficits in the prefrontal cortex, but there is heterogeneity in findings and it is unclear whether findings apply to psychopaths, non-violent offenders, community-based samples, and studies employing psychiatric controls. A meta-analysis was conducted on 43 structural and functional imaging studies and results show significantly reduced prefrontal structure and function in antisocial individuals. Effect sizes were significant for both structural and functional studies. With minor exceptions, no statistically significant moderating effects of sample characteristics and methodological variables were observed. Findings were localized to the right orbitofrontal cortex, right anterior cingulate cortex, and left dorsolateral prefrontal cortex. Findings confirm the replicability of prefrontal structural and functional impairments in antisocial populations and highlight the involvement of orbitofrontal, dorsolateral frontal, and anterior cingulate cortex in antisocial behavior.
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DOI：
10.3109/10401239609147750
发表时间：
1996-09-01
期刊：
Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
影响因子：
--
作者：
Amen, D G;Stubblefield, M;Thisted, R
通讯作者：
Thisted, R
影响因子：
7.6
作者：
GOYER, PF;COHEN, RM;SCHULZ, SC
通讯作者：
SCHULZ, SC
影响因子：
17.7
作者：
Frankle, WG;Lombardo, I;Siever, LJ
通讯作者：
Siever, LJ
影响因子：
2.7
作者：
Barkataki, I;Kumari, V;Sharma, T
通讯作者：
Sharma, T
影响因子：
2.3
作者：
George, DT;Rawlings, RR;Hommer, D
通讯作者：
Hommer, D