Prevalence and risk factors of dry eye syndrome in a United States veterans affairs population.
Prevalence and risk factors of dry eye syndrome in a United States veterans affairs population.
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DOI：
10.1016/j.ajo.2011.02.026
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发表时间：
2011-09
影响因子：
4.2
通讯作者：
Perez, Victor L.
中科院分区：
文献类型：
--
作者：
Galor, Anat;Feuer, William;Lee, David J.;Florez, Hermes;Carter, David;Pouyeh, Bozorgmehr;Prunty, William J.;Perez, Victor L.
评估接受眼部护理服务的美国退伍军人事务部人群中干眼综合征（DES）的患病率及其相关风险因素。回顾性研究。2005年至2010年间，患者在迈阿密和布劳沃德退伍军人事务部眼科诊所就诊。根据干眼症状态将患者分为病例组和对照组（病例= ICD 9编码DES+干眼症治疗;对照组=无ICD 9编码+无治疗的患者）。DES的患病率及其相关危险因素。共有16862例患者被确定为干眼病例（n = 2056）或对照组（n = 14806）。总体而言，12%的男性和22%的女性患者诊断为DES，女性比男性风险增加2.40（95%置信区间[CI] 2.04-2.81）。研究发现，包括创伤后应激障碍在内的几种疾病会增加DES的风险（比值比[OR] 1.97，95% CI 1.75-2.23），抑郁（OR 1.91，95% CI 1.73-2.10）、甲状腺疾病（OR 1.81，95% CI 1.46-2.26）和睡眠呼吸暂停（OR 2.20，95% CI 1.97-2.46）（所有分析均根据性别和年龄进行调整）。使用几种全身性药物，包括抗抑郁药物（OR 1.97，95% CI 1.79-2.17）、抗焦虑药物（OR 1.74，95% CI 1.58-1.91）和抗良性前列腺增生药物（OR 1.68，95% CI 1.51-1.86），同样与DES风险增加相关。在我们的眼科护理人群中，DES的患病率在男性和女性中都很高。这是第一项证明在退伍军人群体中，几种诊断与DES显著相关的研究，包括创伤后应激障碍和抑郁症。
To evaluate the prevalence of dry eye syndrome (DES) and its associated risk factors in a US Veterans Affairs population receiving ocular care services. Retrospective study. Patients were seen in the Miami and Broward Veterans Affairs eye clinics between 2005 and 2010. Patients were divided into cases and controls with regard to their dry eye status (cases = ICD9 code for DES plus dry eye therapy; controls = patients without ICD9 code plus no therapy). The prevalence of DES and its associated risk factors. A total of 16 862 patients were identified as either a dry eye case (n = 2056) or control (n = 14 806). Overall, 12% of male and 22% of female patients had a diagnosis of DES, with female gender imparting a 2.40 increased risk (95% confidence interval [CI] 2.04–2.81) over male gender. Several medical conditions were found to increase DES risk including post-traumatic stress disorder (odds ratio [OR] 1.97, 95% CI 1.75–2.23), depression (OR 1.91, 95% CI 1.73–2.10), thyroid disease (OR 1.81, 95% CI 1.46–2.26), and sleep apnea (OR 2.20, 95% CI 1.97–2.46) (all analyses adjusted for gender and age). The use of several systemic medications, including anti-depressant medications (OR 1.97, 95% CI 1.79–2.17), anti-anxiety medication (OR 1.74, 95% CI 1.58–1.91), and anti–benign prostatic hyperplasia medications (OR 1.68, 95% CI 1.51–1.86), was likewise associated with an increased risk of DES. The prevalence of DES was found to be high in both men and women in our eye care population. This is the first study to demonstrate that in a veteran population, several diagnoses were significantly associated with DES, including post-traumatic stress disorder and depression.
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影响因子：
2.8
作者：
Shimmura, S;Shimazaki, J;Tsubota, K
通讯作者：
Tsubota, K
影响因子：
4
作者：
Chia, EM;Mitchell, P;Wang, JJ
通讯作者：
Wang, JJ
影响因子：
13.7
作者：
Schiffman, RM;Walt, JG;Sumner, W
通讯作者：
Sumner, W
影响因子：
2.8
作者：
Lekhanont, Kaevalin;Rojanaporn, Duangnate;Vongthongsri, Anun
通讯作者：
Vongthongsri, Anun
影响因子：
13.7
作者：
McCarty, CA;Bansal, AK;Taylor, HR
通讯作者：
Taylor, HR