Motion compensated self supervised deep learning for highly accelerated 3D ultrashort Echo time pulmonary MRI.

Motion compensated self supervised deep learning for highly accelerated 3D ultrashort Echo time pulmonary MRI.
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DOI:
10.1002/mrm.29586
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发表时间:
2023-06
影响因子:
3.3
通讯作者:
Johnson KM
Johnson KM
中科院分区:
医学3区
文献类型:
--
作者:
Miller Z;Johnson KM

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研究运动补偿、自我监督、基于模型的深度学习(MBDL)作为重建自由呼吸、3D肺超短回波时间(UTE)采集的方法。开发了一种自监督的超维MBDL架构(XD-MBDL),该架构结合呼吸状态以重建单个高质量3D图像。非刚性的,基于GPU的运动场被纳入到这个架构中,通过估计运动场从一个较低的分辨率运动分辨(XD-GRASP)迭代重建。在有和没有造影剂的肺UTE数据集上评价了运动补偿的XD-MBDL,并将其与不考虑动态呼吸状态或利用运动校正的自监督MBDL的约束重建和变体进行了比较。使用XD-MBDL重建的图像表现出改善的图像质量,如通过表观SNR、CNR和视觉评估测量的,相对于不考虑动态呼吸状态的自监督MBDL方法、XD-GRASP和最近提出的运动补偿迭代重建策略(iMoCo)。此外,相对于XD-GRASP和iMoCo,XD-MBDL减少了重建时间。开发了一种允许自监督MBDL联合收割机组合多个呼吸状态以重建单个图像的方法。将该方法与基于GPU的图像配准相结合,进一步提高了重建质量。该方法显示了从自由呼吸3D肺部UTE采集重建用户选择的呼吸相位的有希望的结果。
To investigate motion compensated, self-supervised, model based deep learning (MBDL) as a method to reconstruct free breathing, 3D Pulmonary ultrashort echo time (UTE) acquisitions. A self-supervised eXtra Dimension MBDL architecture (XD-MBDL) was developed that combined respiratory states to reconstruct a single high-quality 3D image. Non-rigid, GPU based motion fields were incorporated into this architecture by estimating motion fields from a lower resolution motion resolved (XD-GRASP) iterative reconstruction. Motion Compensated XD-MBDL was evaluated on lung UTE datasets with and without contrast and was compared to constrained reconstructions and variants of self-supervised MBDL that do not account for dynamic respiratory states or leverage motion correction. Images reconstructed using XD-MBDL demonstrate improved image quality as measured by apparent SNR, CNR and visual assessment relative to self-supervised MBDL approaches that do not account for dynamic respiratory states, XD-GRASP and a recently proposed motion compensated iterative reconstruction strategy (iMoCo). Additionally, XD-MBDL reduced reconstruction time relative to both XD-GRASP and iMoCo. A method was developed to allow self-supervised MBDL to combine multiple respiratory states to reconstruct a single image. This method was combined with GPU-based image registration to further improve reconstruction quality. This approach showed promising results reconstructing a user-selected respiratory phase from free breathing 3D pulmonary UTE acquisitions.
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