Effects of Thermal Conditioning on Changes in Hepatic and Muscular Tissue Associated With Reduced Heat Production and Body Temperature in Young Chickens.
Effects of Thermal Conditioning on Changes in Hepatic and Muscular Tissue Associated With Reduced Heat Production and Body Temperature in Young Chickens.
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DOI：
10.3389/fvets.2020.610319
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发表时间：
2020
影响因子：
3.2
通讯作者：
Bungo T
中科院分区：
文献类型：
--
作者：
Ouchi Y;Chowdhury VS;Cockrem JF;Bungo T
由于全球变暖，夏季气温升高对家禽生产的影响变得越来越明显，因此考虑可能减少鸡热应激的方法非常重要。在新生期的鸡热调节可以提高耐热性，并减少当鸟类在生命后期暴露于高环境温度时的体温升高。本研究的目的是探讨生理和分子的变化与产热，因此体温调节在高温环境下的热条件下的鸡。通过暴露于高环境温度（40°C）12小时对三日龄的肉仔鸡（Chunky）进行热调节，而对照雏鸡保持在30°C。治疗后4天，两组均暴露于40°C 15或90分钟。直肠温度在90分钟的暴露于高环境温度的增加是热条件比对照鸡少。在15分钟的再曝光处理，解偶联蛋白和肉毒碱棕榈酰转移酶1，产热和脂肪酸氧化的关键分子的基因表达显着较高，在胸肌的控制鸡，但没有条件鸡。再次暴露于高温后，肝脏氨基琥珀酸合成酶（ASS）降低，肝脏氨基琥珀酸裂解酶（ASL）升高。与对照鸡相比，在条件鸡中肝琥珀酸的浓度以及ASS和ASL表达上调，表明尿素循环的活性可以增强，以捕获更多的能量，从而减少条件鸡的产热。这些结果表明，热调节可以减少在高环境温度下发生的鸡肌肉产热增加，以促进显热损失。调理还可以通过改变产热系统来促进肝脏中的能量捕获过程，从而缓解体温的过度升高。
Effects of increased summer temperatures on poultry production are becoming more pronounced due to global warming, so it is important to consider approaches that might reduce heat stress in chickens. Thermal conditioning in chickens in the neonatal period can improve thermotolerance and reduce body temperature increases when birds are exposed to high ambient temperature later in life. The objective of this study was to investigate physiological and molecular changes associated with heat production and hence body temperature regulation under high ambient temperatures in thermally conditioned chicks. Three-day-old broiler chicks (Chunky) were thermally conditioned by exposure to a high ambient temperature (40°C) for 12 h while control chicks were kept at 30°C. Four days after the treatment, both groups were exposed to 40°C for 15 or 90 min. The increase in rectal temperature during 90 min of exposure to a high ambient temperature was less in thermally conditioned than control chicks. At 15-min of re-exposure treatment, gene expression for uncoupling protein and carnitine palmitoyletransferase 1, key molecules in thermogenesis and fatty acid oxidation, were significantly higher in pectoral muscle of control chicks but not conditioned chicks. Hepatic argininosuccinate synthase (ASS) decreased and hepatic argininosuccinate lyase (ASL) increased after reexposure to a high temperature. The concentrations of hepatic arginosuccinic acid, and ASS and ASL expression, were upregulated in conditioned chicks compared with the control chicks, indicating activity of the urea cycle could be enhanced to trap more energy to reduce heat production in conditioned chicks. These results suggest thermal conditioning can reduce the increase in heat production in muscles of chickens that occurs in high ambient temperatures to promote sensible heat loss. Conditioning may also promote energy trapping process in the liver by altering the heat production system, resulting in an alleviation of the excessive rise of body temperature.
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影响因子：
4.4
作者：
De Basilio, V;Vilariño, M;Picard, M
通讯作者：
Picard, M
影响因子：
2.8
作者：
Chen, Zhuo-Yu;Gan, Jian-Kang;Luo, Qing-Bin
通讯作者：
Luo, Qing-Bin
影响因子：
2.7
作者：
Chowdhury, Vishwajit S.;Han, Guofeng;Furuse, Mitsuhiro
通讯作者：
Furuse, Mitsuhiro
DOI：
10.1016/j.cbpb.2009.02.012
发表时间：
2009-06-01
影响因子：
2.2
作者：
Collin, A.;Swennen, Q.;Tesseraud, S.
通讯作者：
Tesseraud, S.
DOI：
10.1152/ajpregu.2001.281.1.r302
发表时间：
2001-07-01
影响因子：
2.8
作者：
Halevy, O;Krispin, A;Yahav, S
通讯作者：
Yahav, S