Biomaterials to enhance stem cell transplantation.
Biomaterials to enhance stem cell transplantation.
复制标题
促进干细胞移植的生物材料。
DOI:
10.1016/j.stem.2022.04.002
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发表时间:
2022-05-05
期刊:
影响因子:
23.9
通讯作者:
Desai, Tejal A.
中科院分区:
文献类型:
--
作者:
Kharbikar, Bhushan N.;Mohindra, Priya;Desai, Tejal A.
The successful transplantation of stem cells has the potential to transform regenerative medicine approaches and open promising avenues to repair, replace, and regenerate diseased, damaged, or aged tissues. However, pre-/post-transplantation issues of poor cell survival, retention, cell fate regulation, and insufficient integration with host tissues constitute significant challenges. The success of stem cell transplantation depends upon the coordinated sequence of stem cell renewal, specific lineage differentiation, assembly, and maintenance of long-term function. Advances in biomaterials can improve pre-/post-transplantation outcomes by integrating biophysiochemical cues and emulating tissue microenvironments. This review highlights leading biomaterials-based approaches for enhancing stem cell transplantation.
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影响因子:
28.1
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Anderson DG
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2.2
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14
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通讯作者:
Bulte, Jeff W. M.
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3.7
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Visai L