Making a head: Neural crest and ectodermal placodes in cranial sensory development.

Making a head: Neural crest and ectodermal placodes in cranial sensory development.
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DOI:
10.1016/j.semcdb.2022.06.009
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发表时间:
2023-03-30
影响因子:
7.3
通讯作者:
Bronner, Marianne E.
Bronner, Marianne E.
中科院分区:
生物学2区
文献类型:
--
作者:
Koontz, Alison;Urrutia, Hugo A.;Bronner, Marianne E.

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在脊椎动物感觉系统的发育过程中,许多重要的组成部分,如感觉器官和颅感觉神经节,出现在头部和颈部。两个祖先群体,即神经嵴和颅外胚层基板,对这些发育中的脊椎动物外周感觉结构做出了贡献。这些细胞群对晶状体、嗅觉、耳、垂体和颅神经节发育的相互作用和贡献对于周围神经系统的适当发育至关重要。在这里,我们回顾了早期脊椎动物胚胎神经板边缘的神经嵴和基板细胞的起源,并研究了影响不同感觉区域规范的分子和环境信号。最后,我们从进化的角度讨论了从基础脊椎动物到羊膜动物对复杂脊椎动物感觉系统做出贡献的潜在分子途径。
During development of the vertebrate sensory system, many important components like the sense organs and cranial sensory ganglia arise within the head and neck. Two progenitor populations, the neural crest, and cranial ectodermal placodes, contribute to these developing vertebrate peripheral sensory structures. The interactions and contributions of these cell populations to the development of the lens, olfactory, otic, pituitary gland, and cranial ganglia are vital for appropriate peripheral nervous system development. Here, we review the origins of both neural crest and placode cells at the neural plate border of the early vertebrate embryo and investigate the molecular and environmental signals that influence specification of different sensory regions. Finally, we discuss the underlying molecular pathways contributing to the complex vertebrate sensory system from an evolutionary perspective, from basal vertebrates to amniotes.
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