Gender, age and geographical representation over the past 50 years of schizophrenia research.
Gender, age and geographical representation over the past 50 years of schizophrenia research.
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DOI：
10.1016/j.psychres.2021.114279
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发表时间：
2022-01
影响因子：
11.3
通讯作者：
ANDES Network
中科院分区：
文献类型：
--
作者：
Alliende LM;Czepielewski LS;Aceituno D;Castañeda CP;Diaz C;Iruretagoyena B;Mena C;Mena C;Ramirez-Mahaluf JP;Tepper Á;Vasquez J;Fonseca L;Machado V;Hernández CE;Vargas-Upegui C;Gomez-Cruz G;Kobayashi-Romero LF;Moncada-Habib T;Evans-Lacko S;Bressan R;Gama CS;Lopez-Jaramillo C;de la Fuente-Sandoval C;Gonzalez-Valderrama A;Undurraga J;Gadelha A;Crossley NA;ANDES Network
先前的研究表明，参与精神分裂症研究的受试者不能代表全球精神分裂症患者的人口统计数据，特别是在性别和地理位置方面。我们在这里探讨了这种情况是否在过去几十年中发生了变化，检查了过去 50 年发表的精神分裂症研究中参与者的地理位置、性别和年龄的变化。我们使用元分析方法对现有数据库进行了检查，其中包括为另一个项目整理的 3,000 多项研究。我们发现，随着时间的推移，来自中低收入国家的研究和参与者的比例显着增加，其中来自中国的研究投入相当大。然而，与他们所代表的全球人口相比，这一数字仍然很低。历史上，女性在研究中的代表性不足，而且在高收入国家仍然如此。然而，随着时间的推移，参与研究的女性参与者比例显着提高。随着时间的推移，参与者的年龄没有发生显着变化。总体而言，精神分裂症患者的地域和性别代表性有所改善。然而，要使研究能够代表全球精神分裂症患者群体，特别是在地理方面，还有很长的路要走。
Previous studies have suggested that subjects participating in schizophrenia research are not representative of the demographics of the global population of people with schizophrenia, particularly in terms of gender and geographical location. We here explored if this has evolved throughout the decades, examining changes in geographical location, gender and age of participants in studies of schizophrenia published in the last 50 years. We examined this using a meta-analytical approach on an existing database including over 3,000 studies collated for another project. We found that the proportion of studies and participants from low-and-middle income countries has significantly increased over time, with considerable input from studies from China. However, it is still low when compared to the global population they represent. Women have been historically under-represented in studies, and still are in high-income countries. However, a significantly higher proportion of female participants have been included in studies over time. The age of participants included has not changed significantly over time. Overall, there have been improvements in the geographical and gender representation of people with schizophrenia. However, there is still a long way to go so research can be representative of the global population of people with schizophrenia, particularly in geographical terms.
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