Evaluation of a skeletal muscle energy convertor in a chronic animal model.
Evaluation of a skeletal muscle energy convertor in a chronic animal model.
复制标题
慢性动物模型中骨骼肌能量转换器的评估。
DOI:
10.1097/00002480-200007000-00023
复制
发表时间:
2000
期刊:
影响因子:
--
通讯作者:
Hill,JD
中科院分区:
文献类型:
--
作者:
Reichenbach,SH;Gustafson,KJ;Egrie,GD;Weidman,JR;Farrar,DJ;Hill,JD
A device is under development for powering cardiac assist devices with skeletal muscle contracting in a linear configuration by converting muscle work to hydraulic energy. Prototype devices are being implanted in goats to study device performance and associated muscle mechanics. Percutaneous hydraulic lines provide the means to control muscle load and evaluate muscle performance during an electrical conditioning protocol. Chronic implant durations ranged from 36 to 87 days in 7 goats. The latissimus dorsi muscle (LDM) insertion was reconnected to the device with a tendon loop. A sternal plate attached with bone screws, and a rib clamp secured the device. A new modular sternal mount design was implemented to eliminate plate loosening that complicated early implants. Extensive bone remodeling around the rib clamp was observed. The tendon attachment demonstrated sufficient initial strength; however, in five implants, efforts to repair the tendon were required. Device encapsulation was observed, but the device continued to cycle freely and no tethering adhesions to the device were found. Interactions between the capsule wall and LDM seemed to limit LDM movement in some cases. Development of a long-term animal model for energy convertor evaluations is an important step toward skeletal muscle powered cardiac assist.
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DOI:
10.1097/00002480-199809000-00091
发表时间:
1998
期刊:
ASAIO journal (American Society for Artificial Internal Organs : 1992)
影响因子:
--
作者:
Reichenbach,SH;Gustafson,KJ;Khazalpour,KM;Farrar,DJ;Hill,JD
通讯作者:
Hill,JD
影响因子:
4.2
作者:
E. Tatsumi;T. Masuzawa;Y. Sohn;S. Endo;T. Ohno;K. Takiura;T. Nishimura;Y. Takewa;Y. Wakisaka;H. Takano
通讯作者:
H. Takano
DOI:
10.1016/0003-4975(94)00528-f
发表时间:
1995
期刊:
The Annals of thoracic surgery
影响因子:
--
作者:
M. Takahashi;T. Misaki;G. Watanabe;H. Ohtake;Y. Tsunezuka;M. Wada;N. Sakakibara;Y. Matsunaga;M. Kawasuji;Y. Watanabe
通讯作者:
Y. Watanabe
DOI:
10.1016/s0003-4975(96)00738-2
发表时间:
1996
期刊:
The Annals of thoracic surgery
影响因子:
--
作者:
Thomas,GA;Isoda,S;Hammond,RL;Lu,H;Nakajima,H;Nakajima,HO;Greer,K;Gilroy,SJ;Salmons,S;Stephenson,LW
通讯作者:
Stephenson,LW
影响因子:
3.3
作者:
D. Trumble;James A. Magovern
通讯作者:
James A. Magovern