THE DIMENSIONALITY OF GENETIC VARIATION FOR WING SHAPE IN DROSOPHILA MELANOGASTER

THE DIMENSIONALITY OF GENETIC VARIATION FOR WING SHAPE IN DROSOPHILA MELANOGASTER
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果蝇翅膀形状遗传变异的维度

DOI:
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发表时间:
2005
期刊:
Evolution; international journal of organic evolution
影响因子:
--
通讯作者:
D. Houle
D. Houle
中科院分区:
--
文献类型:
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作者:
J. Mezey;D. Houle

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摘要 绝对约束是对遗传变异的限制,阻止表型某些方面的进化变化。绝对约束可能反映完全不存在变异、缺乏使表型范围超出一定限度的遗传变异、或缺乏加性遗传变异。最后一种绝对约束是双向的,因为平均值不能变得更大或更小。大多数性状确实具有遗传变异,因此双向绝对约束最有可能在多变量背景下被检测到,它们将反映性状的组合或表型空间中无法进化的维度。双向绝对约束将导致加性遗传协方差矩阵 (G) 的等级小于所研究的性状数量。在这项研究中,我们估计了果蝇翅膀形状 20 个方面的 G 矩阵的等级。我们对两性矩阵秩的最佳估计均为 20。排名的较低 95% 置信区间对于女性为 17,对于男性为 18。因此,我们几乎没有发现双向绝对约束的证据。我们讨论了这一结果对于解决果蝇翅膀形状进化中选择和漂移过程与约束的相对作用的重要性。
Abstract Absolute constraints are limitations on genetic variation that preclude evolutionary change in some aspect of the phenotype. Absolute constraints may reflect complete absence of variation, lack of genetic variation that extends the range of phenotypes beyond some limit, or lack of additive genetic variation. This last type of absolute constraint is bidirectional, because the mean cannot evolve to be larger or smaller. Most traits do possess genetic variation, so bidirectional absolute constraints are most likely to be detected in a multivariate context, where they would reflect combinations of traits, or dimensions in phenotype space that cannot evolve. A bidirectional absolute constraint will cause the additive genetic covariance matrix (G) to have a rank less than the number of traits studied. In this study, we estimate the rank of the G-matrix for 20 aspects of wing shape in Drosophila melanogaster. Our best estimates of matrix rank are 20 in both sexes. Lower 95% confidence intervals of rank are 17 for females and 18 for males. We therefore find little evidence of bidirectional absolute constraints. We discuss the importance of this result for resolving the relative roles of selection and drift processes versus constraints in the evolution of wing shape in Drosophila.
DOI: 10.1093/genetics/130.2.345
发表时间: 1992
期刊: Genetics
影响因子: 3.3
作者:
Weber,KE
通讯作者: Weber,KE
DOI: 10.1093/genetics/126.4.975
发表时间: 1990
期刊: Genetics
影响因子: 3.3
作者:
Weber,KE
通讯作者: Weber,KE
DOI: --
发表时间: 2001-11
期刊: Genetics
影响因子: 3.3
作者:
K. Weber;R. Eisman;S. Higgins;L. Morey;A. Patty;M. Tausek;Z. Zeng
通讯作者: K. Weber;R. Eisman;S. Higgins;L. Morey;A. Patty;M. Tausek;Z. Zeng
DOI: --
发表时间: 1992
期刊: Genetics
影响因子: 3.3
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通讯作者: D. Houle
影响果蝇 3 号染色体翅膀形状的多基因分析。
DOI: 10.1093/genetics/153.2.773
发表时间: 1999
期刊: Genetics
影响因子: 3.3
作者:
Weber,K;Eisman,R;Morey,L;Patty,A;Sparks,J;Tausek,M;Zeng,ZB
通讯作者: Zeng,ZB