Specializations for reward-guided decision-making in the primate ventral prefrontal cortex.
Specializations for reward-guided decision-making in the primate ventral prefrontal cortex.
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DOI：
10.1038/s41583-018-0013-4
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
Rudebeck PH
中科院分区：
文献类型：
--
作者：
Murray EA;Rudebeck PH
选择的估计值以及基于这些值的决策，受到获得所选物品或商品的机会（可用性）和其当前价值（需求性）以及将估计值与选择联系起来的能力（有时称为信用分配的过程）的影响。在灵长类动物中，前额皮质（PFC）被认为对这些过程都有贡献。然而，PFC 的特定分支与特定功能之间的因果关系很难建立。最近基于损伤的研究定义了灵长类前额皮层的两个不同部分——眶额皮层（OFC）和腹外侧额叶皮层（VLFC）——及其细分在评估这些因素以及在基于奖励的决策过程中调解信用分配方面的作用。
The estimated values of choices, and therefore decision making based on those values, is influenced by both the chance that the chosen items or goods can be obtained (availability) and their current worth (desirability) as well as the ability to link the estimated values to choices (a process sometimes called credit assignment). In primates, the prefrontal cortex (PFC) has been thought to contribute to each of these processes; however, causal relationships between particular subdivisions of the PFC and specific functions have been difficult to establish. Recent lesion-based research studies have defined the roles of two different parts of the primate PFC — the orbitofrontal cortex (OFC) and the ventral lateral frontal cortex (VLFC) — and their subdivisions in evaluating each of these factors and in mediating credit assignment during reward-based decision making.
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影响因子：
3.7
作者：
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通讯作者：
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