Wearable Technology for Chronic Wound Monitoring: Current Dressings, Advancements, and Future Prospects.
Wearable Technology for Chronic Wound Monitoring: Current Dressings, Advancements, and Future Prospects.
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DOI：
10.3389/fbioe.2018.00047
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发表时间：
2018
影响因子：
5.7
通讯作者：
Koh A
中科院分区：
文献类型：
--
作者：
Brown MS;Ashley B;Koh A
慢性不愈合伤口挑战组织再生，并损害患有这种病症的患者的感染调节。能够原位生理监测的下一代伤口护理技术可以诊断伤口参数，治疗各种慢性伤口症状，并通过使用闭环治疗系统非侵入性地减少伤口处的感染，这将为患者提供改进的护理标准和加速的伤口修复机制。慢性伤口特异性的指示性生物标志物包括血压、温度、氧气、pH、乳酸盐、葡萄糖、白细胞介素-6（IL-6）和感染状态。伤口监测设备将有助于减少长期住院、多次看医生以及与慢性伤口的诊断和治疗相关的昂贵的实验室测试。非常需要一种能够监测伤口状态并刺激愈合过程的装置。在这篇综述中，我们讨论了慢性伤口受损的生理状态，并解释了目前的治疗方法。具体而言，我们专注于可穿戴设备的材料，平台，制造方法的改进，以及对伤口愈合进展至关重要的各种生物标志物的定量分析。
Chronic non-healing wounds challenge tissue regeneration and impair infection regulation for patients afflicted with this condition. Next generation wound care technology capable of in situ physiological surveillance which can diagnose wound parameters, treat various chronic wound symptoms, and reduce infection at the wound noninvasively with the use of a closed loop therapeutic system would provide patients with an improved standard of care and an accelerated wound repair mechanism. The indicating biomarkers specific to chronic wounds include blood pressure, temperature, oxygen, pH, lactate, glucose, interleukin-6 (IL-6), and infection status. A wound monitoring device would help decrease prolonged hospitalization, multiple doctors' visits, and the expensive lab testing associated with the diagnosis and treatment of chronic wounds. A device capable of monitoring the wound status and stimulating the healing process is highly desirable. In this review, we discuss the impaired physiological states of chronic wounds and explain the current treatment methods. Specifically, we focus on improvements in materials, platforms, fabrication methods for wearable devices, and quantitative analysis of various biomarkers vital to wound healing progress.
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影响因子：
12.6
作者：
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通讯作者：
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DOI：
10.4000/abpo.2524
发表时间：
2012-01-01
期刊：
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发表时间：
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影响因子：
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