Zinc-based alloys for degradable vascular stent applications.
Zinc-based alloys for degradable vascular stent applications.
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DOI：
10.1016/j.actbio.2018.03.005
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发表时间：
2018-04-15
影响因子：
9.7
通讯作者：
Vedani M
中科院分区：
文献类型：
--
作者：
Mostaed E;Sikora-Jasinska M;Drelich JW;Vedani M
寻找机械性能等于或高于目前使用的永久性生物材料（例如不锈钢、钴铬和钛合金）的机械性能、期望的体内降解速率和均匀腐蚀的可生物降解的金属仍然是一个开放的挑战。已经提出镁（Mg）、铁（Fe）和锌（Zn）基合金作为用于医疗应用的可生物降解金属。在过去的二十年里，对Mg和Fe进行了广泛的研究。铁基合金表现出适当的力学性能，但其降解速率比基准值低一个数量级。相比之下，除了其大多数合金的机械性能不足之外，镁在生理环境中的降解速率被证明过高，并且腐蚀很少均匀。在过去的几年中，锌合金已被探索的生物医学界作为潜在的材料，生物可吸收血管支架由于其可容忍的腐蚀速率和可调的机械性能。本文综述了近年来锌合金在血管支架应用中的研究进展。新型锌合金的微观结构特征，机械性能，腐蚀行为和在体内的性能进行了讨论。
The search for biodegradable metals with mechanical properties equal or higher to those of currently used permanent biomaterials, such as stainless steels, cobalt chromium and titanium alloys, desirable in vivo degradation rate and uniform corrosion is still an open challenge. Magnesium (Mg), iron (Fe) and zinc (Zn)-based alloys have been proposed as biodegradable metals for medical applications. Over the last two decades, extensive research has been done on Mg and Fe. Fe-based alloys show appropriate mechanical properties, but their degradation rate is an order of magnitude below the benchmark value. In comparison, alongside the insufficient mechanical performance of most of its alloys, Mg degradation rate has proven to be too high in a physiological environment and corrosion is rarely uniform. During the last few years, Zn alloys have been explored by the biomedical community as potential materials for bioabsorbable vascular stents due to their tolerable corrosion rates and tunable mechanical properties. This review summarizes recent progress made in developing Zn alloys for vascular stenting application. Novel Zn alloys are discussed regarding their microstructural characteristics, mechanical properties, corrosion behavior and in vivo performance.
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影响因子：
2.2
作者：
Buenger, Carsten Michael;Grabow, Niels;Schareck, Wolfgang
通讯作者：
Schareck, Wolfgang
DOI：
10.1016/j.msec.2016.11.138
发表时间：
2017-04-01
影响因子：
7.9
作者：
Bakhsheshi-Rad, H. R.;Hamzah, E.;Cho, M. H.
通讯作者：
Cho, M. H.
影响因子：
3.9
作者：
Falk, T;Svensson, JE;Johansson, LG
通讯作者：
Johansson, LG
DOI：
10.1016/j.msec.2015.07.022
发表时间：
2015-11-01
期刊：
Materials science & engineering. C, Materials for biological applications
影响因子：
--
作者：
Bowen PK;Guillory RJ 2nd;Shearier ER;Seitz JM;Drelich J;Bocks M;Zhao F;Goldman J
通讯作者：
Goldman J
影响因子：
4.1
作者：
Dahl, SG;Allain, P;Christiansen, C
通讯作者：
Christiansen, C