Recent Nanotechnology Approaches for Prevention and Treatment of Biofilm-Associated Infections on Medical Devices.

Recent Nanotechnology Approaches for Prevention and Treatment of Biofilm-Associated Infections on Medical Devices.
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最新的纳米技术方法用于预防和治疗医疗设备上与生物膜相关的感染。

DOI:
10.1155/2016/1851242
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发表时间:
2016
影响因子:
--
通讯作者:
Lee J
Lee J
中科院分区:
生物学3区
文献类型:
--
作者:
Ramasamy M;Lee J

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表面上生物膜形式的细菌定植导致持续感染,并且是医疗保健提供者相当关注的问题。迫切需要新型的抗微生物或抗微生物膜表面和生物医学装置,其提供针对生物膜形成和病原体(包括抗生素抗性菌株)的保护。在此背景下,材料科学和工程领域的最新发展以及纳米技术领域的稳步进展为设计具有抗感染、抗菌、杀菌和抗微生物膜特性的新生物材料和表面创造了机会。在这里,我们回顾了一些最近开发的纳米技术为基础的生物材料,并解释基本的战略,用于使纳米薄膜表面。
Bacterial colonization in the form of biofilms on surfaces causes persistent infections and is an issue of considerable concern to healthcare providers. There is an urgent need for novel antimicrobial or antibiofilm surfaces and biomedical devices that provide protection against biofilm formation and planktonic pathogens, including antibiotic resistant strains. In this context, recent developments in the material science and engineering fields and steady progress in the nanotechnology field have created opportunities to design new biomaterials and surfaces with anti-infective, antifouling, bactericidal, and antibiofilm properties. Here we review a number of the recently developed nanotechnology-based biomaterials and explain underlying strategies used to make antibiofilm surfaces.
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