Visual function and serous retinal detachment in patients with branch retinal vein occlusion and macular edema: a case series.

Visual function and serous retinal detachment in patients with branch retinal vein occlusion and macular edema: a case series.
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DOI:
10.1186/1471-2415-11-29
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发表时间:
2011-09-26
期刊:
影响因子:
2
通讯作者:
Shimada K
Shimada K
中科院分区:
医学4区
文献类型:
--
作者:
Noma H;Funatsu H;Mimura T;Shimada K

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浆液性视网膜脱离(SRD)对视网膜分支静脉阻塞(BRVO)和黄斑水肿患者视网膜敏感度的影响尚不清楚。尽管在光学相干断层扫描(OCT)上BRVO患者中SRD和囊样黄斑水肿(CME)频繁共存,并且CME是继发于BRVO的黄斑水肿的最常见形式。我们研究了BRVO和黄斑水肿患者的视功能(视力和黄斑敏感度)、黄斑厚度和黄斑体积。根据光学相干断层扫描结果,将53例连续BRVO患者(26例女性和27例男性)分为两组。采用显微视野计测量黄斑功能,OCT测量黄斑厚度和黄斑体积,其中SRD 15例,CME 38例。15例SRD患者中有14例同时患有CME。SRD组的视力明显差于CME组(P = 0.049)。此外,SRD组中心4°、10°和20°视野内的黄斑厚度和黄斑体积显著更大(分别为P = 0.008和P = 0.007,P < 0.001和P < 0.001,P < 0.001和P < 0.001)。然而,在中心4°、10°和20°视野内,SRD组的黄斑敏感性并不显著差于CME组。SRD本身可能与CME一起降低视力,因为几乎所有的SRD患者都有CME。SRD似乎不影响微视野检查的黄斑功能。
The influence of serous retinal detachment (SRD) on retinal sensitivity in patients with branch retinal vein occlusion (BRVO) and macular edema remains unclear. This is despite the frequent co-existence of SRD and cystoid macular edema (CME) in BRVO patients on optical coherence tomography (OCT) and the fact that CME is the most common form of macular edema secondary to BRVO. We investigated visual function (visual acuity and macular sensitivity), macular thickness, and macular volume in patients with BRVO and macular edema. Fifty-three consecutive BRVO patients (26 women and 27 men) were divided into two groups based on optical coherence tomography findings. Macular function was documented by microperimetry, while macular thickness and volume were measured by OCT. There were 15 patients with SRD and 38 patients with CME. Fourteen of the 15 patients with SRD also had CME. Visual acuity was significantly worse in the SRD group than in the CME group (P = 0.049). Also, macular thickness and macular volume within the central 4°, 10°, and 20° fields were significantly greater in the SRD group (P = 0.008, and P = 0.007, P < 0.001 and P < 0.001, and P < 0.001 and P < 0.001, respectively). However, macular sensitivity within the central 4°, 10°, and 20° fields was not significantly worse in the SRD group than in the CME group. SRD itself may decrease visual acuity together with CME, because nearly all SRD patients also had CME. SRD does not seem to influence macular function on microperimetry.
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