Design and application of nanoparticles as vaccine adjuvants against human corona virus infection.
Design and application of nanoparticles as vaccine adjuvants against human corona virus infection.
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纳米粒子作为抗人冠状病毒感染疫苗佐剂的设计与应用
DOI:
10.1016/j.jinorgbio.2021.111454
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发表时间:
2021-06
影响因子:
3.9
通讯作者:
Chen C
中科院分区:
文献类型:
--
作者:
Mao L;Chen Z;Wang Y;Chen C
In recent years, some viruses have caused a grave crisis to global public health, especially the human coronavirus. A truly effective vaccine is therefore urgently needed. Vaccines should generally have two features: delivering antigens and modulating immunity. Adjuvants have an unshakable position in the battle against the virus. In addition to the perennial use of aluminium adjuvant, nanoparticles have become the developing adjuvant candidates due to their unique properties. Here we introduce several typical nanoparticles and their antivirus vaccine adjuvant applications. Finally, for the combating of the coronavirus, we propose several design points, hoping to provide ideas for the development of personalized vaccines and adjuvants and accelerate the clinical application of adjuvants. Several typical nanoparticles are potential candidates for vaccine adjuvants, protecting human beings from coronavirus infections.
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影响因子:
7.8
作者:
George, Parakkal Jovvian;Tai, Wanbo;Lustigman, Sara
通讯作者:
Lustigman, Sara
影响因子:
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DOI:
10.1073/pnas.1911734116
发表时间:
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影响因子:
11.1
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通讯作者:
MAURER, PH