Quality of life after surgery for intracranial meningioma.
Quality of life after surgery for intracranial meningioma.
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DOI：
10.1002/cncr.30975
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发表时间：
2018-01-01
期刊：
影响因子：
6.2
通讯作者：
Claus EB
中科院分区：
文献类型：
--
作者：
Benz LS;Wrensch MR;Schildkraut JM;Bondy ML;Warren JL;Wiemels JL;Claus EB
关于诊断为颅内脑膜瘤的患者的长期生活质量（QOL）的数据有限。这些数据来自2006年5月1日至2013年3月14日康涅狄格州、马萨诸塞州、加州、德克萨斯州和北卡罗来纳州居民中诊断的1722例脑膜瘤病例，以及1622例按年龄、性别和地理位置与病例频率匹配的对照。这些人是一项大型的、基于人群的病例/对照研究的参与者。使用医疗结局研究（MOS-36），通过电话采访收集初步诊断或联系时的QOL数据。通过病例/对照状态比较QOL结局。诊断为脑膜瘤的患者报告的身体，情绪和心理健康功能水平低于一般健康人群。病例参与者和对照组在身体和社会功能、角色-身体、角色-情感和活力方面差异最显著。脑膜瘤患者的生活质量与具有相似人口统计学特征的健康对照组相比有统计学意义的下降，尽管这些差异在临床意义上各不相同。与类似人口统计学分类的健康对照相比，脑膜瘤患者的生活质量在统计学上显著下降，最明显的是在身体和社会功能，角色-身体，角色-情感和活力方面。然而，这些差异在临床意义上各不相同。
Limited data exist on long-term quality of life (QOL) for patients diagnosed with intracranial meningioma. The data are on 1722 meningioma cases diagnosed among residents of Connecticut, Massachusetts, California, Texas, and North Carolina from May 1, 2006 through March 14, 2013 and 1622 controls frequency matched to the cases by age, sex and geography. These individuals were participants in a large, population-based case/control study. Telephone interviews were used to collect data on QOL at time of initial diagnosis or contact, using the Medical Outcomes Study (MOS-36). QOL outcomes were compared by case/control status. Patients diagnosed with meningioma report levels of physical, emotional, and mental health functioning below those reported in a general healthy population. Case participants and controls differed most significantly in the domains of physical and social functioning, role-physical, role-emotional and vitality. Patients with meningioma experience statistically significant decreases in quality of life compared to a healthy control of similar demographic breakdown, though these differences vary in clinical significance. Patients with meningioma experience statistically significant decreases in quality of life compared to a healthy control of similar demographic breakdown, most notably in the domains of physical and social functioning, role-physical, role-emotional and vitality. These differences, however, vary in clinical significance.
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影响因子：
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