Polymer composition and substrate influences on the adhesive bonding of a biomimetic, cross-linking polymer.
Polymer composition and substrate influences on the adhesive bonding of a biomimetic, cross-linking polymer.
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DOI：
10.1021/ja303369p
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发表时间：
2012-06-06
影响因子：
15
通讯作者：
Wilker, Jonathan J.
中科院分区：
文献类型：
--
作者：
Matos-Perez, Cristina R.;White, James D.;Wilker, Jonathan J.
骨骼、贝壳和海洋生物粘合剂等分层生物材料为合成分子组装成复杂结构提供了灵感。近年来，贻贝的粘合系统一直备受关注。几种含儿茶酚的聚合物正在开发中，以模拟贝类用于粘附岩石的含有 3,4-二羟基苯丙氨酸 (DOPA) 的蛋白质的交联。许多仿生聚合物系统已被证明可以形成表面涂层或水凝胶，但很少有人证明其整体粘附性。开发粘合剂需要解决设计问题，包括在内聚力和粘合相互作用之间找到良好的平衡。尽管仿贻贝聚合物的数量不断增加，但人们却很少努力去建立结构-性能关系，并深入了解哪些化学特性可以产生最好的胶水。在本报告中，我们研究了这些仿生聚合物中最简单的一种，聚[(3,4-二羟基苯乙烯)-苯乙烯]。儿茶酚侧基（即 3,4-二羟基苯乙烯）分布在整个聚苯乙烯主链上。制备了几种聚合物衍生物，每种具有不同的 3,4-二羟基苯乙烯含量。整体粘合力测试显示了内聚力和粘合剂粘合的最佳中间位置。粘合性能以商业胶水以及活贻贝生产的真实材料为基准。在最好的情况下，粘合类似于氰基丙烯酸酯“Krazy”或“Super”胶。还使用低能（例如塑料）和高能（例如金属、木材）表面检查了性能。聚[(3,4-二羟基苯乙烯)-苯乙烯共聚物]的粘合可能是已报道的贻贝蛋白模拟物中最强的。这些见解应该有助于我们设计未来的仿生系统，从而使我们更接近骨水泥、牙科复合材料和手术胶水的开发。
Hierarchical biological materials such as bone, sea shells, and marine bioadhesives are providing inspiration for the assembly of synthetic molecules into complex structures. The adhesive system of marine mussels has been the focus of much attention in recent years. Several catechol-containing polymers are being developed to mimic the cross-linking of proteins containing 3,4-dihydroxyphenylalanine (DOPA) used by shellfish for sticking to rocks. Many of these biomimetic polymer systems have been shown to form surface coatings or hydrogels, however bulk adhesion is demonstrated less often. Developing adhesives requires addressing design issues including finding a good balance between cohesive and adhesive bonding interactions. Despite the growing number of mussel mimicking polymers, there has been little effort to generate structure-property relations and gain insights on what chemical traits give rise to the best glues. In this report, we examined the simplest of these biomimetic polymers, poly[(3,4-dihydroxystyrene)-co-styrene]. Pendant catechol groups (i.e., 3,4-dihydroxystyrene) were distributed throughout a polystyrene backbone. Several polymer derivatives were prepared, each with a different 3,4-dihyroxystyrene content. Bulk adhesion testing showed where the optimal middle ground of cohesive and adhesive bonding resides. Adhesive performance was benchmarked against commercial glues as well as the genuine material produced by live mussels. In the best case, bonding was similar to cyanoacrylate “Krazy” or “Super” glue. Performance was also examined using low (e.g., plastics) and high (e.g., metals, wood) energy surfaces. Adhesive bonding of poly[(3,4-dihydroxystyrene)-co-styrene] may be the strongest of reported mussel protein mimics. These insights should help us to design future biomimetic systems, thereby bringing us closer to development of bone cements, dental composites, and surgical glues.
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影响因子：
2.7
作者：
Cha, Hyung Joon;Hwang, Dong Soo;Wilker, Jonathan J.
通讯作者：
Wilker, Jonathan J.
DOI：
10.1088/1748-6041/6/1/015014
发表时间：
2011-02
期刊：
Biomedical materials (Bristol, England)
影响因子：
--
作者：
Brodie M;Vollenweider L;Murphy JL;Xu F;Lyman A;Lew WD;Lee BP
通讯作者：
Lee BP
抗微生物涂层的儿茶酚功能将两亲和固定的固定。
DOI：
10.1021/la1046904
发表时间：
2011-04-05
期刊：
Langmuir : the ACS journal of surfaces and colloids
影响因子：
--
作者：
Han H;Wu J;Avery CW;Mizutani M;Jiang X;Kamigaito M;Chen Z;Xi C;Kuroda K
通讯作者：
Kuroda K
影响因子：
14
作者：
Brubaker, Carrie E.;Kissler, Hermann;Wang, Ling-Jia;Kaufman, Dixon B.;Messersmith, Phillip B.
通讯作者：
Messersmith, Phillip B.
影响因子：
4.7
作者：
Bae, Ki Hyun;Kim, Young Beom;Park, Tae Gwan
通讯作者：
Park, Tae Gwan