Effect of CaCl2 hydrothermal treatment on the bone bond strength and osteoconductivity of Ti–0.5Pt and Ti–6Al–4V–0.5Pt alloy implants

Effect of CaCl2 hydrothermal treatment on the bone bond strength and osteoconductivity of Ti–0.5Pt and Ti–6Al–4V–0.5Pt alloy implants
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CaCl2水热处理对Ti-0.5Pt和Ti-6Al-4V-0.5Pt合金种植体骨结合强度和骨传导性的影响

DOI:
10.1007/s10856-009-3799-9
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发表时间:
2009
期刊:
Journal of Materials Science: Materials in Medicine
影响因子:
--
通讯作者:
Jyunichi Yamazoe
Jyunichi Yamazoe
中科院分区:
--
文献类型:
--
作者:
M. Nakagawa;Jyunichi Yamazoe

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为了实现骨传导性,将Ti-0.5Pt和Ti-6Al-4V-0.5Pt合金在200°C下在10 mmol/l CaCl 2水溶液中水热处理24 h(HT处理)。我们使用Wistar大鼠(SD大鼠)对HT处理的材料进行组织学研究,以评估处理的有效性。为测量骨结合强度,将样本植入SD大鼠胫骨中,并进行拔出试验。从术后早期阶段开始,HT处理的种植体获得了直接骨接触。在植入1-4周内,HT处理的种植体的骨接触率和骨结合强度高于未处理的种植体。HT处理的Ti-0.5Pt和Ti-6Al-4V-0.5Pt合金显示出开发具有高骨结合强度和快速骨传导的新植入物的潜力。
To achieve osteoconductivity, Ti–0.5Pt and Ti–6Al–4V–0.5Pt alloys were hydrothermally treated at 200°C in 10 mmol/l CaCl2 aqueous solution for 24 h (HT-treatment). We conducted histological investigations of the HT-treated materials by using Wistar strain rats (SD rats) to evaluate the usefulness of the treatment. To measure the bone bond strength, the specimens were implanted in the tibia of SD rats, and a pull-out test was conducted. From the early postoperative stages, direct bone contact was obtained for the HT-treated implants. Within 1–4 weeks of implantation, the bone contact ratios and bone bond strengths of the HT-treated implants were higher than those of the non-treated implants. The Ti–0.5Pt and Ti–6Al–4V–0.5Pt alloys with HT-treatment showed the potential to develop a new implant with a high bone bond strength and rapid osteoconduction.
T. Mano:“使用喷砂涂层方法在室温下对涂有磷灰石的钛植入物进行初始组织反应”生物材料。
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