Human parechovirus infection, Denmark.

Human parechovirus infection, Denmark.
复制标题

DOI:
10.3201/eid2001.130569
复制
发表时间:
2014-01
影响因子:
11.8
通讯作者:
Nielsen AY
Nielsen AY
中科院分区:
医学2区
文献类型:
--
作者:
Fischer TK;Midgley S;Dalgaard C;Nielsen AY

文献摘要

参考文献

被引文献

相似文献

应对所有怀疑患有HPeV或肠道病毒感染的幼儿进行HPeV检测。人类parechovirus (HPeVs)常在幼儿中引起严重疾病。2009年1月至2012年12月期间,在丹麦所有县对所有脑脊液、粪便和组织样本进行了常规检测的国家监测(对来自4,804名儿童的6,817个样本进行了HPeV筛查)。我们在149人的202份(3.0%)标本中检测到HPeV RNA。幼儿感染HPeV的风险最高,9(6%)感染HPeV的儿童死亡,可能死于他们的HPeV疾病。HPeV3是最常见的基因型,在整个研究期间,丹麦有5个密切相关的HPeV3分支。我们的研究增加了对HPeV感染的患病率、临床和分子病毒学特征的看法。
HPeV should be tested for in all young children suspected to have HPeV or enterovirus infection. Human parechoviruses (HPeVs) often cause severe illness among young children. National surveillance with routine testing of all cerebrospinal fluid, fecal, and tissue samples was conducted during January 2009–December 2012 in all counties in Denmark (6,817 samples from 4,804 children were screened for HPeV). We detected HPeV RNA in 202 (3.0%) specimens from 149 persons. Young infants were at highest risk for HPeV, and 9 (6%) of the HPeV-infected children died, probably of their HPeV illness. HPeV3 was the most common genotype identified, and 5 closely related clades of HPeV3 circulated in Denmark throughout the study period. Our study adds perspective on the prevalence and clinical and molecular virologic characteristics of HPeV infection.
DOI: 10.1086/589752
发表时间: 2008-08-01
影响因子: 11.8
作者:
Wolthers, Katja C.;Benschop, Kimberley S. M.;Pajkrt, Dasja
通讯作者: Pajkrt, Dasja
DOI: 10.3201/eid1811.111570
发表时间: 2012-11
影响因子: 11.8
作者:
Mizuta K;Kuroda M;Kurimura M;Yahata Y;Sekizuka T;Aoki Y;Ikeda T;Abiko C;Noda M;Kimura H;Mizutani T;Kato T;Kawanami T;Ahiko T
通讯作者: Ahiko T
DOI: 10.1128/jcm.01207-08
发表时间: 2008-10-01
影响因子: 9.4
作者:
Harvala, H.;Robertson, I.;Simmonds, P.
通讯作者: Simmonds, P.
DOI: 10.1128/jcm.00168-08
发表时间: 2008-09-01
影响因子: 9.4
作者:
van der Sanden, Sabine;de Bruin, Erwin;van der Avoort, Harrie
通讯作者: van der Avoort, Harrie
DOI: 10.1002/jmv.23197
发表时间: 2012-04-01
影响因子: 12.7
作者:
Piralla, Antonio;Furione, Milena;Baldanti, Fausto
通讯作者: Baldanti, Fausto