A custom magnetoencephalography device reveals brain connectivity and high reading/decoding ability in children with autism.
A custom magnetoencephalography device reveals brain connectivity and high reading/decoding ability in children with autism.
复制标题
自闭症儿童的定制磁脑摄影设备揭示了大脑连通性和高读数/解码能力。
DOI：
10.1038/srep01139
复制
发表时间：
2013
影响因子：
4.6
通讯作者：
Minabe, Yoshio
中科院分区：
文献类型：
--
作者：
Kikuchi, Mitsuru;Yoshimura, Yuko;Shitamichi, Kiyomi;Ueno, Sanae;Hirosawa, Tetsu;Munesue, Toshio;Ono, Yasuki;Tsubokawa, Tsunehisa;Haruta, Yasuhiro;Oi, Manabu;Niida, Yo;Remijn, Gerard B.;Takahashi, Tsutomu;Suzuki, Michio;Higashida, Haruhiro;Minabe, Yoshio
自闭症谱系障碍（ASD）患者的一个子集在某些视觉任务上的表现比他们的一般认知表现所预测的更熟练。然而，在患有ASD的年幼儿童（5至7岁）中，这些任务的保留能力及其能力的神经生理学相关性没有得到很好的记录。在本研究中，我们使用了一个定制的儿童大小的脑磁图系统，并证明了在视觉推理任务中保留的能力与ASD儿童顶叶和颞叶区域之间的神经生理连接的单侧化有关。此外，我们证明了更高的阅读/解码能力也与ASD儿童相同的偏侧化相关。视觉任务的这些神经生理相关性与在正常发育的儿童中观察到的相关性有很大不同。这些发现表明，ASD儿童具有固有的不同神经通路，这有助于他们相对保留视觉任务的能力。
A subset of individuals with autism spectrum disorder (ASD) performs more proficiently on certain visual tasks than may be predicted by their general cognitive performances. However, in younger children with ASD (aged 5 to 7), preserved ability in these tasks and the neurophysiological correlates of their ability are not well documented. In the present study, we used a custom child-sized magnetoencephalography system and demonstrated that preserved ability in the visual reasoning task was associated with rightward lateralisation of the neurophysiological connectivity between the parietal and temporal regions in children with ASD. In addition, we demonstrated that higher reading/decoding ability was also associated with the same lateralisation in children with ASD. These neurophysiological correlates of visual tasks are considerably different from those that are observed in typically developing children. These findings indicate that children with ASD have inherently different neural pathways that contribute to their relatively preserved ability in visual tasks.
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DOI：
10.1017/s1355617708081356
发表时间：
2008-11-01
影响因子：
2.6
作者：
Keehn, Brandon;Brenner, Laurie;Mueller, Ralph-Axel
通讯作者：
Mueller, Ralph-Axel
DOI：
10.1126/science.1171402
发表时间：
2009-05-29
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Gregoriou GG;Gotts SJ;Zhou H;Desimone R
通讯作者：
Desimone R
影响因子：
14.5
作者：
Just, MA;Cherkassky, VL;Minshew, NJ
通讯作者：
Minshew, NJ
影响因子：
6.9
作者：
Charman, T.;Pickles, A.;Baird, G.
通讯作者：
Baird, G.
影响因子：
14.5
作者：
Anderson, Jeffrey S.;Nielsen, Jared A.;Lainhart, Janet E.
通讯作者：
Lainhart, Janet E.