Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: A systematic review.

Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: A systematic review.
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心理社会和精神病合并症以及与健康相关的生活质量的脱发:系统评价。

DOI:
10.1016/j.jaad.2020.06.047
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发表时间:
2021-07
影响因子:
13.8
通讯作者:
Kiuru M
Kiuru M
中科院分区:
医学1区
文献类型:
--
作者:
Toussi A;Barton VR;Le ST;Agbai ON;Kiuru M

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斑秃(AA)是一种免疫介导的疾病,导致非瘢痕性脱发。关于心理社会和精神共病、健康相关生活质量和针对心理社会健康的干预措施的系统评价有限。对成人和儿童AA患者的心理社会共病、健康相关生活质量和针对心理社会健康的治疗选择进行系统性综述。根据PubMed数据库中系统性综述和荟萃分析(PRISMA)指南的首选报告项目进行系统性综述。具体检索词包括但不限于斑秃、社会心理学、精神病学和生活质量。然后根据牛津循证医学中心的指导原则,对研究的设计进行评估,并将其归类为相应的证据等级。73份报告符合纳入标准,涉及约414,319名独立参与者。AA患者被发现有精神共病,特别是焦虑和抑郁。AA患者的健康相关生活质量降低,但有关儿童AA生活质量的数据有限。心理治疗通常被推荐作为辅助治疗。AA对患者有很大的心理社会影响,并导致健康相关的生活质量降低。解决这个问题应该是治疗的一个积极部分。
Alopecia areata (AA) is an immune-mediated disease resulting in nonscarring hair loss. Systematic reviews on the psychosocial and psychiatric comorbidities, health-related quality of life, and interventions targeting psychosocial well-being are limited. To conduct a systematic review of the psychosocial comorbidities, health-related quality of life, and treatment options targeting psychosocial well-being in adult and pediatric AA patients. A systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines within the PubMed database. Specific search terms included, but were not limited to, alopecia areata, psychosocial, psychiatry, and quality of life. Studies were then evaluated for their design and categorized into corresponding levels of evidence according to the guidelines adapted from the Oxford Center for Evidence Based Medicine. Seventy-three reports met inclusion criteria, involving approximately 414,319 unique participants. AA patients were found to have psychiatric comorbidities, particularly anxiety and depression. Health-related quality of life is reduced in AA patients, but data on pediatric AA quality of life are limited. Psychotherapy is often recommended as adjuvant treatment. AA has substantial psychosocial impact on patients and results in reduced health-related quality of life. Addressing this should be an active part of treatment.
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