Immune and inflammatory mechanisms of abdominal aortic aneurysm.
Immune and inflammatory mechanisms of abdominal aortic aneurysm.
复制标题
腹主动脉瘤的免疫和炎症机制。
DOI:
10.3389/fimmu.2022.989933
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发表时间:
2022
影响因子:
7.3
通讯作者:
Koltsova, Ekaterina K.
中科院分区:
文献类型:
--
作者:
Marquez-Sanchez, Ana Cristina;Koltsova, Ekaterina K.
关键词:
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-mediated infiltration and a destruction of the aortic wall during AAA development plays significant role in the pathogenesis of this disease. While various immune cells had been found in AAA, the mechanisms of their activation and function are still far from being understood. A better understanding of mechanisms regulating the development of aberrant immune cell activation in AAA is essential for the development of novel preventive and therapeutic approaches. In this review we summarize current knowledge about the role of immune cells in AAA and discuss how pathogenic immune cell activation is regulated in this disease.
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影响因子:
7.7
作者:
Cani, Patrice D.;Amar, Jacques;Burcelin, Remy
通讯作者:
Burcelin, Remy
影响因子:
30.3
作者:
Araujo, Joao R.;Tazi, Asmaa;Sansonetti, Philippe J.
通讯作者:
Sansonetti, Philippe J.
影响因子:
8.3
作者:
Barhoumi, Tlili;Kasal, Daniel A.;Schiffrin, Ernesto L.
通讯作者:
Schiffrin, Ernesto L.
影响因子:
10.8
作者:
Burger F;Miteva K;Baptista D;Roth A;Fraga-Silva RA;Martel C;Stergiopulos N;Mach F;Brandt KJ
通讯作者:
Brandt KJ
影响因子:
4
作者:
Barp CG;Bonaventura D;Assreuy J
通讯作者:
Assreuy J