No significant association between COVID-19 diagnosis and the incidence of depression and anxiety disorder? A retrospective cohort study conducted in Germany.
No significant association between COVID-19 diagnosis and the incidence of depression and anxiety disorder? A retrospective cohort study conducted in Germany.
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DOI：
10.1016/j.jpsychires.2022.01.013
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发表时间：
2022-03
影响因子：
4.8
通讯作者：
Kostev K
中科院分区：
文献类型：
--
作者：
Jacob L;Koyanagi A;Smith L;Bohlken J;Haro JM;Kostev K
与其他呼吸道感染相比，人们对 2019 年冠状病毒病 (COVID-19) 对心理健康的影响知之甚少。因此，这项回顾性队列研究的目的是调查与急性上呼吸道感染诊断相比，在德国接受全科治疗的患者中，COVID-19 诊断是否与抑郁症和焦虑症发病率显着增加相关。这项研究纳入了 2020 年 3 月至 2021 年 5 月期间在德国 1198 家全科诊所中首次诊断出有症状或无症状 COVID-19 的所有患者。使用基于性别、年龄、指数月份和查尔森合并症指数的倾向评分将诊断为急性上呼吸道感染的患者与 COVID-19 患者进行匹配。索引日期与诊断出 COVID-19 或急性上呼吸道感染的日期相对应。使用条件泊松回归模型研究了 COVID-19 和急性上呼吸道感染组之间抑郁症和焦虑症发病率的差异。这项研究包括 56,350 名被诊断为 COVID-19 的患者和 56,350 名被诊断为急性上呼吸道感染的患者（52.3% 为女性；平均 [SD] 年龄 43.6 [19.2] 岁）。 COVID-19组的抑郁症（IRR = 1.02，95% CI = 0.95–1.10）和焦虑障碍（IRR = 0.94，95% CI = 0.83–1.07）的发生率并不显着高于上呼吸道感染组。与急性上呼吸道感染诊断相比，在德国接受全科治疗的患者中，COVID-19 诊断与抑郁症和焦虑症发病率的显着增加无关。
Little is known about the effects of coronavirus disease 2019 (COVID-19) on mental health compared with other respiratory infections. Thus, the aim of this retrospective cohort study was to investigate whether COVID-19 diagnosis is associated with a significant increase in the incidence of depression and anxiety disorder in patients followed in general practices in Germany compared with acute upper respiratory infection diagnosis. This study included all patients diagnosed with symptomatic or asymptomatic COVID-19 for the first time in 1198 general practices in Germany between March 2020 and May 2021. Patients diagnosed with acute upper respiratory infection were matched to those with COVID-19 using propensity scores based on sex, age, index month, and Charlson Comorbidity Index. The index date corresponded to the date on which either COVID-19 or acute upper respiratory infection was diagnosed. Differences in the incidence of depression and anxiety disorder between the COVID-19 and the acute upper respiratory infection group were studied using conditional Poisson regression models. This study included 56,350 patients diagnosed with COVID-19 and 56,350 patients diagnosed with acute upper respiratory infection (52.3% women; mean [SD] age 43.6 [19.2] years). The incidence of depression (IRR = 1.02, 95% CI = 0.95–1.10) and anxiety disorder (IRR = 0.94, 95% CI = 0.83–1.07) was not significantly higher in the COVID-19 group than in the upper respiratory infection group. Compared with acute upper respiratory infection diagnosis, COVID-19 diagnosis was not associated with a significant increase in the incidence of depression and anxiety disorder in patients treated in general practices in Germany.
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影响因子：
7.4
作者：
Krawczyk K;Chelkowski T;Laydon DJ;Mishra S;Xifara D;Gibert B;Flaxman S;Mellan T;Schwämmle V;Röttger R;Hadsund JT;Bhatt S
通讯作者：
Bhatt S
影响因子：
4.5
作者：
Ayouni I;Maatoug J;Dhouib W;Zammit N;Fredj SB;Ghammam R;Ghannem H
通讯作者：
Ghannem H
DOI：
10.1136/jnnp-2021-327565
发表时间：
2021-12
期刊：
Journal of neurology, neurosurgery, and psychiatry
影响因子：
--
作者：
Klaser K;Thompson EJ;Nguyen LH;Sudre CH;Antonelli M;Murray B;Canas LS;Molteni E;Graham MS;Kerfoot E;Chen L;Deng J;May A;Hu C;Guest A;Selvachandran S;Drew DA;Modat M;Chan AT;Wolf J;Spector TD;Hammers A;Duncan EL;Ourselin S;Steves CJ
通讯作者：
Steves CJ
DOI：
10.1016/s0140-6736(21)01755-4
发表时间：
2021-08-28
期刊：
Lancet (London, England)
影响因子：
--
作者：
Huang L;Yao Q;Gu X;Wang Q;Ren L;Wang Y;Hu P;Guo L;Liu M;Xu J;Zhang X;Qu Y;Fan Y;Li X;Li C;Yu T;Xia J;Wei M;Chen L;Li Y;Xiao F;Liu D;Wang J;Wang X;Cao B
通讯作者：
Cao B
影响因子：
2.6
作者：
Jones, Simon;Mason, Neil;Horwitz, Leora, I
通讯作者：
Horwitz, Leora, I