Framing the Drivers of Antimicrobial Resistance in Tanzania.

Framing the Drivers of Antimicrobial Resistance in Tanzania.
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DOI:
10.3390/antibiotics10080991
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发表时间:
2021-08-16
期刊:
Antibiotics (Basel, Switzerland)
影响因子:
--
通讯作者:
Legido-Quigley H
Legido-Quigley H
中科院分区:
其他
文献类型:
--
作者:
Durrance-Bagale A;Jung AS;Frumence G;Mboera L;Mshana SE;Sindato C;Clark TG;Matee M;Legido-Quigley H

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尽管全球都认识到抗菌素耐药性 (AMR) 的关键因素,但设计和实施政策来解决 AMR 驱动因素的关键问题在实践中仍然很复杂。我们确定了坦桑尼亚参与应对抗微生物药物耐药性的认识论界所使用的流行叙述和框架,探讨了该框架如何为政策制定提供信息,并确定了可以针对被认为对抗微生物药物耐药性负有责任的群体量身定制的干预措施。我们采访了来自三个地区的 114 名关键知情人,并逐行分析了笔录。我们的结果表明,许多不同的群体帮助推动了坦桑尼亚抗微生物药物耐药性的传播,需要参与任何有效的应对措施。目前,人类健康被认为是应对措施的推动者,而其他领域的努力则落后了。为了使抗微生物药物耐药性项目取得成功,所有部门都需要参与,包括民间社会团体、社区代表和社区工作人员(例如初级保健医生)。然而,当前的计划和方案基本上没有包含这些观点。坦桑尼亚明显表现出了政治意愿,这是朝着这一回应迈出的重要一步。任何应对抗菌素耐药性的战略都需要根据具体情况进行调整,同时考虑到各国内部的限制、信仰和权力动态。
Despite global awareness of the key factors surrounding antimicrobial resistance (AMR), designing and implementing policies to address the critical issues around the drivers of AMR remains complex to put into practice. We identified prevalent narratives and framing used by epistemological communities involved in the response to AMR in Tanzania, interrogated how this framing may inform policymaking, and identified interventions that could be tailored to the groups believed responsible for AMR. We interviewed 114 key informants from three districts and analysed transcripts line by line. Our results suggest that many different groups help drive the spread of AMR in Tanzania and need to be involved in any effective response. Human health is currently perceived as driving the response, while other domains lag behind in their efforts. For AMR programmes to be successful, all sectors need to be involved, including civil society groups, community representatives, and those working in communities (e.g., primary care physicians). However, current plans and programmes largely fail to include these viewpoints. The perceived presence of political will in Tanzania is a significant step towards such a response. Any strategies to tackle AMR need to be tailored to the context-specific realities, taking into account constraints, beliefs, and power dynamics within countries.
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