Effects of adipokinetic hormone and its related peptide on maintaining hemolymph carbohydrate and lipid levels in the two-spotted cricket, Gryllus bimaculatus
Effects of adipokinetic hormone and its related peptide on maintaining hemolymph carbohydrate and lipid levels in the two-spotted cricket, Gryllus bimaculatus
复制标题
脂肪运动激素及其相关肽对维持双斑蟋蟀血淋巴碳水化合物和脂质水平的影响
DOI:
10.1080/09168451.2017.1422106
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发表时间:
2018
期刊:
影响因子:
--
通讯作者:
Nagata Shinji
中科院分区:
文献类型:
--
作者:
Zhou Yi Jun;Fukumura Keisuke;Nagata Shinji
Adipokinetic hormone (AKH) regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Here, using RNA sequencing data, we identified cDNAs encodingAKH(GbAKH) and its highly homologous hormoneAKH/corazonin-related peptide(GbACP) in the corpora cardiaca of the two-spotted cricket,Gryllus bimaculatus. RT-PCR revealed thatGbAKHandGbACPare predominantly expressed in the corpora cardiaca and corpora allata, respectively. Phylogenetic analysis confirmed that the identified GbAKH and GbACP belong to the clades containing other AKHs and ACPs, respectively. Injection of synthetic GbAKH and GbACP elevated hemolymph carbohydrate and lipid levels and reduced food intake significantly. In contrast, knockdown ofGbAKHandGbACPby RNA interference increased the food intake, although hemolymph lipid level was not altered. Collectively, this study provides evidence that ACP regulates hemolymph carbohydrate and lipid levels in cricket, possibly collaborative contribution with AKH to the maintenance of energy homeostasis.
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影响因子:
2.2
作者:
D. Kodrík;R. Socha;Z. Syrová
通讯作者:
Z. Syrová
影响因子:
1.5
作者:
M. Lorenz;R. Zemek;D. Kodrík;R. Socha
通讯作者:
M. Lorenz;R. Zemek;D. Kodrík;R. Socha
影响因子:
2.2
作者:
Ziegler,R
通讯作者:
Ziegler,R
影响因子:
--
作者:
G. Goldsworthy;C. Wheeler
通讯作者:
C. Wheeler
DOI:
10.1016/s1095-6433(02)00134-4
发表时间:
2002
期刊:
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
影响因子:
--
作者:
J. Woodring;M. Lorenz;K. Hoffmann
通讯作者:
K. Hoffmann