Identification and adjustment of experimental occlusal interference using functional magnetic resonance imaging.
Identification and adjustment of experimental occlusal interference using functional magnetic resonance imaging.
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DOI：
10.1186/1472-6831-14-124
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发表时间：
2014-10-10
期刊：
影响因子：
2.9
通讯作者：
Morimoto Y
中科院分区：
文献类型：
--
作者：
Oda M;Yoshino K;Tanaka T;Shiiba S;Makihara E;Miyamoto I;Nogami S;Kito S;Wakasugi-Sato N;Matsumoto-Takeda S;Nishimura S;Murakami K;Koga M;Kawagishi S;Yoshioka I;Masumi S;Kimura M;Morimoto Y
本研究的目的是使用功能性磁共振成像（fMRI）来量化实验性咬合干扰期间大脑活动的变化。14名健康志愿者在0 mm（无咬合），0.5 mm和0.75 mm的位置上进行实验性的右磨牙咬合干扰，进行有节奏的叩击咬合任务。使用统计参数映射量化血氧水平依赖（BOLD）信号，并在休息期和任务期之间进行比较。在实验咬合干扰为0.75 mm或0.5 mm的叩击任务中，对侧牙齿相关初级感觉皮层和Brodmann’s 46区被明显激活。在去除实验咬合干扰后0和30分钟，双侧牙齿相关初级感觉皮质和Brodmann’s 46区明显出现激活。在去除实验咬合干扰后60分钟，Brodmann’s 46区的激活消失，只有与双侧牙齿相关的初级感觉皮质活跃。本研究结果表明，利用功能磁共振成像可以客观地评价实验性咬合干扰的调整。我们期望这种评估咬合干扰调整的方法，结合功能磁共振成像和叩击任务，可以在未来的临床应用。
The purpose of this study was to use functional magnetic resonance imaging (fMRI) to quantify changes in brain activity during experimental occlusal interference. Fourteen healthy volunteers performed a rhythmical tapping occlusion task with experimental occlusal interference of the right molar tooth at 0 mm (no occlusion), 0.5 mm, and 0.75 mm. The blood-oxygen-level dependent (BOLD) signal was quantified using statistical parametric mapping and compared between rest periods and task periods. In tapping tasks with experimental occlusal interference of 0.75 mm or 0.5 mm, there was clear activation of the contralateral teeth-related primary sensory cortex and Brodmann’s area 46. At 0 and 30 minutes after removal of the experimental occlusal interference, the activation clearly appeared in the bilateral teeth-related primary sensory cortices and Brodmann’s area 46. At 60 minutes after the removal of the experimental occlusal interference, the activation of Brodmann’s area 46 had disappeared, and only the bilateral teeth-related primary sensory cortices were active. The present results suggest that adjustments for experimental occlusal interference can be objectively evaluated using fMRI. We expect that this method of evaluating adjustments in occlusal interference, combined with fMRI and the tapping task, could be applied clinically in the future.
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