Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man.
Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man.
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DOI:
10.1038/s41583-018-0039-7
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发表时间:
2018-09
期刊:
影响因子:
--
通讯作者:
Suh J
中科院分区:
文献类型:
--
作者:
Fenster RJ;Lebois LAM;Ressler KJ;Suh J
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly consequence of exposure to severe psychological trauma. Although effective treatments exist for some individuals, they are limited. New approaches to intervention, treatment and prevention are therefore much needed. In the past few years, the field has rapidly developed a greater understanding of the dysfunctional brain circuits underlying PTSD, a shift in understanding that has been made possible by technological revolutions that have allowed the observation and perturbation of the macrocircuits and microcircuits thought to underlie PTSD-related symptoms. These advances have allowed us to gain a more translational knowledge of PTSD, have provided further insights into the mechanisms of risk and resilience and offer promising avenues for therapeutic discovery.
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DOI:
10.4088/jcp.08m04638blu
发表时间:
2010-08
期刊:
The Journal of clinical psychiatry
影响因子:
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作者:
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10.6
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影响因子:
10.6
作者:
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影响因子:
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通讯作者:
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