Sympatric chimpanzees and gorillas harbor convergent gut microbial communities.
Sympatric chimpanzees and gorillas harbor convergent gut microbial communities.
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DOI：
10.1101/gr.154773.113
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发表时间：
2013-10
期刊：
影响因子：
7
通讯作者：
Ochman H
中科院分区：
文献类型：
--
作者：
Moeller AH;Peeters M;Ndjango JB;Li Y;Hahn BH;Ochman H
大型类人猿的肠道微生物群落已被证明反映了其宿主的系统发育历史，表明大型类人猿及其肠道微生物群在进化时间尺度上的共同多样性。但是，由于迄今为止所研究的类人猿代表了地理上孤立的种群，它们的饮食来源不同，因此尚不清楚这种共同多样化的模式是由于微生物和宿主之间长期的相互适应（遗传因素），还是由于宿主物种之间的生态和地理分离（环境因素）。为了评估遗传和环境因素对类人猿肠道微生物群进化的相对影响，我们分析了居住在赤道非洲的黑猩猩，倭黑猩猩和大猩猩的同域和异域种群的肠道群落。对这些种群的比较表明，不同宿主物种的肠道群落总是可以相互区分，但同域黑猩猩和大猩猩的肠道群落在群落组成方面已经趋同，平均比异域宿主的肠道群落共享53%以上的细菌群落类型。宿主环境独立于宿主遗传学和进化历史，决定了细菌系统型在拟杆菌门、厚壁菌门、变形菌门和放射菌门（肠道细菌的四个最常见门）中的分布。此外，宿主之间共享细菌类型的特定模式表明，与大猩猩同域生活的黑猩猩从大猩猩那里获得了细菌。这些结果表明，宿主物种之间的地理隔离促进了大猿肠道细菌群落的进化分化。
The gut microbial communities within great apes have been shown to reflect the phylogenetic history of their hosts, indicating codiversification between great apes and their gut microbiota over evolutionary timescales. But because the great apes examined to date represent geographically isolated populations whose diets derive from different sources, it is unclear whether this pattern of codiversification has resulted from a long history of coadaptation between microbes and hosts (heritable factors) or from the ecological and geographic separation among host species (environmental factors). To evaluate the relative influences of heritable and environmental factors on the evolution of the great ape gut microbiota, we assayed the gut communities of sympatric and allopatric populations of chimpanzees, bonobos, and gorillas residing throughout equatorial Africa. Comparisons of these populations revealed that the gut communities of different host species can always be distinguished from one another but that the gut communities of sympatric chimpanzees and gorillas have converged in terms of community composition, sharing on average 53% more bacterial phylotypes than the gut communities of allopatric hosts. Host environment, independent of host genetics and evolutionary history, shaped the distribution of bacterial phylotypes across the Bacteroidetes, Firmicutes, Proteobacteria, and Actinobacteria, the four most common phyla of gut bacteria. Moreover, the specific patterns of phylotype sharing among hosts suggest that chimpanzees living in sympatry with gorillas have acquired bacteria from gorillas. These results indicate that geographic isolation between host species has promoted the evolutionary differentiation of great ape gut bacterial communities.
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DOI：
10.1038/oby.2011.111
发表时间：
2012-04
期刊：
Obesity (Silver Spring, Md.)
影响因子：
--
作者：
Ravussin Y;Koren O;Spor A;LeDuc C;Gutman R;Stombaugh J;Knight R;Ley RE;Leibel RL
通讯作者：
Leibel RL
影响因子：
17.1
作者：
Turnbaugh PJ;Ridaura VK;Faith JJ;Rey FE;Knight R;Gordon JI
通讯作者：
Gordon JI
DOI：
10.1126/science.1198719
发表时间：
2011-05-20
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Muegge BD;Kuczynski J;Knights D;Clemente JC;González A;Fontana L;Henrissat B;Knight R;Gordon JI
通讯作者：
Gordon JI
影响因子：
64.8
作者：
Arumugam, Manimozhiyan;Raes, Jeroen;Pelletier, Eric;Le Paslier, Denis;Yamada, Takuji;Mende, Daniel R.;Fernandes, Gabriel R.;Tap, Julien;Bruls, Thomas;Batto, Jean-Michel;Bertalan, Marcelo;Borruel, Natalia;Casellas, Francesc;Fernandez, Leyden;Gautier, Laurent;Hansen, Torben;Hattori, Masahira;Hayashi, Tetsuya;Kleerebezem, Michiel;Kurokawa, Ken;Leclerc, Marion;Levenez, Florence;Manichanh, Chaysavanh;Nielsen, H. Bjorn;Nielsen, Trine;Pons, Nicolas;Poulain, Julie;Qin, Junjie;Sicheritz-Ponten, Thomas;Tims, Sebastian;Torrents, David;Ugarte, Edgardo;Zoetendal, Erwin G.;Wang, Jun;Guarner, Francisco;Pedersen, Oluf;de Vos, Willem M.;Brunak, Soren;Dore, Joel;Weissenbach, Jean;Ehrlich, S. Dusko;Bork, Peer
通讯作者：
Bork, Peer
影响因子：
24.5
作者：
Serino M;Luche E;Gres S;Baylac A;Bergé M;Cenac C;Waget A;Klopp P;Iacovoni J;Klopp C;Mariette J;Bouchez O;Lluch J;Ouarné F;Monsan P;Valet P;Roques C;Amar J;Bouloumié A;Théodorou V;Burcelin R
通讯作者：
Burcelin R