Selective targeting of biting females to control mosquito-borne infectious diseases.
Selective targeting of biting females to control mosquito-borne infectious diseases.
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DOI:
10.1016/j.pt.2022.05.012
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发表时间:
2022-09
影响因子:
9.6
通讯作者:
Tu, Zhijian
中科院分区:
文献类型:
--
作者:
Kojin, Bianca B.;Compton, Austin;Adelman, Zach N.;Tu, Zhijian
Mosquitoes are vectors for a number of infectious diseases. Only females feed on blood to provision for their embryos and in doing so transmit pathogens to the associated vertebrate hosts. Therefore, sex is an important phenotype in the context of genetic control programs, both for sex separation in the rearing facilities to avoid releasing the biting females and for ways to distort the sex ratio towards the non-biting males. We review recent progress in the fundamental knowledge of sex determination and sex chromosomes in mosquitoes and discuss new methods to achieve sex separation and sex ratio distortion to help control mosquito-borne infectious diseases. We conclude by suggesting a few critical areas for future research.
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