Taste reactivity as a dependent measure of the rapid formation of conditioned taste aversion: a tool for the neural analysis of taste-visceral associations.
Taste reactivity as a dependent measure of the rapid formation of conditioned taste aversion: a tool for the neural analysis of taste-visceral associations.
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味觉反应性作为条件味觉厌恶快速形成的依赖测量：味觉与内脏关联的神经分析工具。
DOI：
10.1037//0735-7044.102.6.942
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发表时间：
1988
影响因子：
1.9
通讯作者：
Grill,HJ
中科院分区：
文献类型：
--
作者：
Spector,AC;Breslin,P;Grill,HJ
有几种解释可以解释动物在神经操纵后形成味觉厌恶的能力的缺陷。这些包括条件刺激（CS）和非条件刺激（US）处理，条件反应（CR）测量，表达，记忆和味觉内脏整合的障碍。一个行为的程序，艾滋病在这些可能性之间的区别。在实验1中，10只大鼠在注射3.0 mEq/kg氯化锂（LiCl）后立即开始每5分钟接受7次蔗糖（30 s，0.55 ml）口内（IO）输注。对照组大鼠（n= 12）进行相同的处理，除了它们注射氯化钠（NaCl）。口腔运动和躯体味觉反应行为进行录像和分析。注射锂的大鼠随着时间的推移系统地降低了他们的摄食味觉反应行为，而厌恶行为增加。对照组大鼠保持高水平和稳定的摄食反应，并表现出几乎没有厌恶的行为超过30分钟后，钠注射。几天后测试大鼠是否存在条件性味觉厌恶（CTA）。先前在蔗糖输注过程中注射锂的大鼠表现出比对照组明显更厌恶的行为，而对照组没有表现出任何行为。在CTA测试中，两组的摄食行为水平没有差异。实验3显示，当在锂诱导状态下对类似处理的大鼠进行CTA测试时，观察到两组之间的摄食行为差异。在实验2中，幼稚大鼠注射氯化钠或氯化锂，但没有收到他们的第一次蔗糖输液，直到20分钟后。这些大鼠还在注射后25和30 min接受蔗糖输注。在任何蔗糖输注过程中，锂或钠注射大鼠的味觉反应行为均无差异。总的来说，这些研究结果表明，大鼠显着改变他们的orrhythmic反应蔗糖在一段时间后，氯化锂管理，提供输注后立即开始注射。此外，这种与时间相关的行为变化主要归因于联想过程。这种模式可以是有用的，在区分神经操作，影响建立味觉内脏协会从其他影响动物的能力，以保持这种协会在常用的24小时条件测试间隔。
Several explanations may account for deficits in the ability of animals to form taste aversions following neural manipulations. These encompass impairments in conditioned stimulus (CS) and unconditioned stimulus (US) processing, conditioned response (CR) measurement, and expression, memory, and taste-visceral integration. A behavioral procedure that aids in the distinction between some of these possibilities is presented. In Experiment 1, 10 rats received seven intraoral (IO) infusions of sucrose (30 s, 0.55 ml) spaced every 5 min starting immediately after the injection of 3.0 mEq/kg of lithium chloride (LiCl). Control rats (n= 12) were treated identically except that they were injected with sodium chloride (NaCl). Oromotor and somatic taste reactivity behaviors were videotaped and analyzed. Lithium-injected rats systematically decreased their ingestive taste reactivity behavior over time, whereas aversive behavior increased. Control rats maintained high and stable levels of ingestive responding and demonstrated virtually no aversive behavior over the 30-min period following sodium injection. Rats were tested several days later for the presence of a conditioned taste aversion (CTA). Rats previously injected with lithium during sucrose infusions demonstrated significantly more aversive behavior than the control group, which demonstrated none. There were no differences in the level of ingestive behavior displayed by the two groups on the CTA test. Experiment 3 revealed that when similarly treated rats were tested for a CTA while in a lithium-induced state, a difference in the ingestive behavior between the two groups was observed. In Experiment 2, naive rats were injected with either NaCl or LiCl but did not receive their first sucrose infusion until 20 min later. These rats also received sucrose infusions at 25 and 30 min postinjection. There were no differences in the taste reactivity behavior displayed by lithium-or sodium-injected rats during any of the sucrose infusions. Collectively, these findings indicate that rats dramatically change their oromotor responses to sucrose during the period following LiCl administration, provided that the infusions start immediately after injection. Furthermore, this time-related behavioral change is predominantly attributable to associative processes. This paradigm can be useful in distinguishing between neural manipulations that affect the establishment of taste-visceral associations from others that affect the animal’s ability to retain such associations over the commonly employed 24-hr conditioning-test interval.
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白化大鼠的恐新症和增强的恐新症演示。
DOI：
--
发表时间：
1975
期刊：
Journal of Comparative and Physiological Psychology
影响因子：
--
作者：
M. Carroll;H. I. Dinc;C. Levy;J. C. Smith
通讯作者：
J. C. Smith
影响因子：
3.6
作者：
BERRIDGE, KC;TREIT, D
通讯作者：
TREIT, D
条件性味觉厌恶：参考书目
DOI：
--
发表时间：
1976
期刊：
影响因子：
--
作者：
A. Riley;Linda L. Baril
通讯作者：
Linda L. Baril
大鼠后区损伤后辐射和药物引起的条件性味觉厌恶的减弱。
影响因子：
3.4
作者：
B. Rabin;W. A. Hunt;J. Lee
通讯作者：
J. Lee
影响因子：
2.9
作者：
S. Ritter;J. McGlone;K. Kelley
通讯作者：
K. Kelley