Early childhood antibiotic utilization for infants discharged from the neonatal intensive care unit.
Early childhood antibiotic utilization for infants discharged from the neonatal intensive care unit.
复制标题
DOI：
10.1038/s41372-022-01380-y
复制
发表时间：
2022-07
影响因子：
2.9
通讯作者：
Puopolo, Karen M.
中科院分区：
文献类型：
--
作者：
Flannery, Dustin D.;Passarella, Molly;Mukhopadhyay, Sagori;Dhudasia, Miren B.;Gerber, Jeffrey S.;Lorch, Scott A.;Hennessy, Sean;Puopolo, Karen M.
确定新生儿重症监护病房婴儿与非新生儿重症监护病房婴儿在出生出院后前3年的抗生素使用情况。回顾性观察性研究使用来自医疗补助分析摘录的数据，包括2007年至2011年出院的667，541名新生儿。使用回归模型评估NICU入院和抗生素处方之间的关系，调整混杂因素，并按胎龄和出生体重分层。596999名婴儿（89.4%）接受了≥1种抗生素治疗，中位处方数为4张/3人-年（IQR 2-8）。两组之间的处方抗生素和相关适应症相似。与非NICU婴儿（N=586 227）相比，NICU婴儿（N=81 314）接受了更多的抗生素处方（校正后的发生率比为1.08，95%置信区间[CI]为（1.08，1.08））。在所有NICU亚组中观察到相似的结果。与非NICU婴儿相比，从NICU出院的婴儿在幼儿期的抗生素利用率较高。
To determine antibiotic utilization for NICU infants, as compared to non-NICU infants, in the first 3 years after birth hospital discharge. Retrospective observational study using data from Medicaid Analytic Extract including 667 541 newborns discharged from 2007–2011. Associations between NICU admission and antibiotic prescription were assessed using regression models, adjusting for confounders, and stratified by gestational age and birth weight. 596 999 infants (89.4%) received ≥1 antibiotic, with a median of 4 prescriptions per 3 person-years (IQR 2–8). Prescribed antibiotics and associated indication were similar between groups. Compared to non-NICU infants (N=586 227), NICU infants (N=81 314) received more antibiotic prescriptions (adjusted incidence rate ratio 1.08, 95% confidence interval [CI] (1.08,1.08)). Similar results were observed in all NICU subgroups. Antibiotic utilization in early childhood was higher among infants discharged from NICUs compared to non-NICU infants.
登录
查看更多内容
DOI：
10.1038/s41372-020-00829-2
发表时间：
2020-11
期刊：
Journal of perinatology : official journal of the California Perinatal Association
影响因子：
--
作者：
Underwood MA;Mukhopadhyay S;Lakshminrusimha S;Bevins CL
通讯作者：
Bevins CL
影响因子：
8
作者：
Alm, Bernt;Erdes, Laslo;Wennergren, Goeran
通讯作者：
Wennergren, Goeran
影响因子：
120.7
作者：
Nyquist, AC;Gonzales, R;Sande, MA
通讯作者：
Sande, MA
影响因子：
5.2
作者：
Chiorean, Andreea;Savoy, Calan;Van Lieshout, Ryan J.
通讯作者：
Van Lieshout, Ryan J.
影响因子：
5.1
作者：
Houweling, Leanne M. A.;Bezemer, Irene D.;Herings, Ron M. C.
通讯作者：
Herings, Ron M. C.