Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study.

Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study.
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芬兰糖尿病预防研究中的休闲时间体力活动和代谢综合征。

DOI:
10.2337/dc09-2155
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发表时间:
2010-07
期刊:
影响因子:
16.2
通讯作者:
Tuomilehto, Jaakko
Tuomilehto, Jaakko
中科院分区:
医学1区
文献类型:
--
作者:
Ilanne-Parikka, Pirjo;Laaksonen, David E.;Eriksson, Johan G.;Lakka, Timo A.;Lindstrom, Jaana;Peltonen, Markku;Aunola, Sirkka;Keinanen-Kiukaanniemi, Sirkka;Uusitupa, Matti;Tuomilehto, Jaakko

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在芬兰糖尿病预防研究(一项随机对照生活方式咨询试验)的事后分析中,评估休闲时间体育活动(LTPA)和阻力训练对代谢综合征(MetS)及其组成部分的影响。对486名患有糖耐量受损的中年超重男性和女性进行了平均4.1年的随访。干预组与对照组合并分析。LTPA每年通过问卷调查、饮食记录的膳食摄入量和人体测量和生化测量的MetS特征来评估。记录了137名参与者的阻力训练课程。即使在调整了总脂肪和饱和脂肪、纤维和能量的膳食摄入量的变化以及BMI的变化之后,中至高强度LTPA的增加与更大的可能性(29.7比19.1%;变化的上三分之一比下三分之一P = 0.004)和更小的可能性(23.5比44.7%;P = 0.041)相关。在代谢当量的组成部分中,中高强度LTPA的增加与血糖的改善密切相关。在137名参加抗阻训练的参与者中,met成分在参与率最高的三分之一(中位数为51次/年)的个体中较低的三分之一(中位数为8.5次/年)的个体有利。在2型糖尿病高危人群中,中高强度LTPA的增加与met发生的可能性降低和其消退的可能性增加有关。
To assess the effects of leisure-time physical activity (LTPA) and resistance training on metabolic syndrome (MetS) and its components in a post hoc analysis of the Finnish Diabetes Prevention Study, a randomized controlled lifestyle counseling trial. A cohort of 486 middle-aged overweight men and women with impaired glucose tolerance were followed for an average of 4.1 years. The intervention and control groups were combined in the analyses. LTPA was assessed by questionnaires, dietary intake by food records, and features of the MetS by anthropometric and biochemical measures annually. Resistance training sessions were documented for 137 participants. Increased moderate-to-vigorous LTPA, even after adjustments for changes in dietary intakes of total and saturated fat, fiber, and energy, and change in BMI was associated with a greater likelihood for resolution (29.7 vs. 19.1%; P = 0.004 in the upper versus lower third of change) and a lesser likelihood for development (23.5 vs. 44.7%; P = 0.041) of the MetS. Of the components of the MetS, the increase in moderate-to-vigorous LTPA was associated most strongly with improvement of glycemia. Among the 137 participants who participated in resistance training, MetS components were favorable in individuals who were in the upper third of participation rate (median 51 times/year) compared with individuals in the lowest third (median 8.5 times/year). Increased moderate-to-vigorous LTPA was associated with a decreased likelihood of developing the MetS and an increased likelihood of its resolution in individuals at high risk for type 2 diabetes.
DOI: 10.2337/diacare.28.5.1195
发表时间: 2005-05-01
期刊: DIABETES CARE
影响因子: 16.2
作者:
Ekelund, U;Brage, S;Wareham, NJ
通讯作者: Wareham, NJ
DOI: 10.2337/diabetes.52.8.2160
发表时间: 2003-08-01
期刊: DIABETES
影响因子: 7.7
作者:
Meigs, JB;Wilson, PWF;Haffner, SM
通讯作者: Haffner, SM
DOI: 10.2337/dc07-1117
发表时间: 2008-04-01
期刊: DIABETES CARE
影响因子: 16.2
作者:
Ilanne-Parikka, Pirjo;Eriksson, Johan G.;Tuomilehto, Jaakko
通讯作者: Tuomilehto, Jaakko
DOI: 10.1001/jama.288.21.2709
发表时间: 2002-12-04
影响因子: 120.7
作者:
Lakka, HM;Laaksonen, DE;Salonen, JT
通讯作者: Salonen, JT
DOI: 10.2337/diacare.28.1.108
发表时间: 2005-01-01
期刊: DIABETES CARE
影响因子: 16.2
作者:
Boulé, NG;Weisnagel, SJ;Bouchard, C
通讯作者: Bouchard, C