Animal studies for the evaluation of in situ tissue-engineered vascular grafts - a systematic review, evidence map, and meta-analysis.
Animal studies for the evaluation of in situ tissue-engineered vascular grafts - a systematic review, evidence map, and meta-analysis.
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DOI：
10.1038/s41536-022-00211-0
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发表时间：
2022-02-23
影响因子：
7.2
通讯作者：
Smits AIPM
中科院分区：
文献类型：
--
作者：
Koch SE;de Kort BJ;Holshuijsen N;Brouwer HFM;van der Valk DC;Dankers PYW;van Luijk JAKR;Hooijmans CR;de Vries RBM;Bouten CVC;Smits AIPM
Vascular in situ tissue engineering (TE) is an approach that uses bioresorbable grafts to induce endogenous regeneration of damaged blood vessels. The evaluation of newly developed in situ TE vascular grafts heavily relies on animal experiments. However, no standard for in vivo models or study design has been defined, hampering inter-study comparisons and translational efficiency. To provide input for formulating such standard, the goal of this study was to map all animal experiments for vascular in situ TE using off-the-shelf available, resorbable synthetic vascular grafts. A literature search (PubMed, Embase) yielded 15,896 studies, of which 182 studies met the inclusion criteria (n = 5,101 animals). The reports displayed a wide variety of study designs, animal models, and biomaterials. Meta-analysis on graft patency with subgroup analysis for species, age, sex, implantation site, and follow-up time demonstrated model-specific variations. This study identifies possibilities for improved design and reporting of animal experiments to increase translational value.
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影响因子：
4.2
作者：
Awad NK;Niu H;Ali U;Morsi YS;Lin T
通讯作者：
Lin T
影响因子：
4.6
作者：
Blum KM;Roby LC;Zbinden JC;Chang YC;Mirhaidari GJM;Reinhardt JW;Yi T;Barker JC;Breuer CK
通讯作者：
Breuer CK
影响因子：
2.4
作者：
de Vries RB;Hooijmans CR;Tillema A;Leenaars M;Ritskes-Hoitinga M
通讯作者：
Ritskes-Hoitinga M
DOI：
10.1002/jbm.a.36013
发表时间：
2017-05
期刊：
Journal of biomedical materials research. Part A
影响因子：
--
作者：
Hachim D;Wang N;Lopresti ST;Stahl EC;Umeda YU;Rege RD;Carey ST;Mani D;Brown BN
通讯作者：
Brown BN
DOI：
10.1515/jbcpp-2018-0002
发表时间：
2018-09-01
影响因子：
--
作者：
Dutta, Sulagna;Sengupta, Pallav
通讯作者：
Sengupta, Pallav