Electrospun Fibrous Scaffolds for Small-Diameter Blood Vessels: A Review.

Electrospun Fibrous Scaffolds for Small-Diameter Blood Vessels: A Review.
复制标题

DOI:
10.3390/membranes8010015
复制
发表时间:
2018-03-06
期刊:
影响因子:
4.2
通讯作者:
Lin T
Lin T
中科院分区:
工程技术4区
文献类型:
--
作者:
Awad NK;Niu H;Ali U;Morsi YS;Lin T

文献摘要

参考文献

被引文献

相似文献

小直径血管(SDBV)由于血栓形成、内膜增生和血管扩张的发生,其制备仍然是一项具有挑战性的任务。静电纺丝技术作为一种很有前途的组织工程方法,可以制备满足天然血管细胞外基质(ECM)构建要求的高分子纤维支架,促进细胞的粘附、增殖和生长。在这篇综述中,我们总结了用于制造SDBV的聚合物,并将其分为三类,合成聚合物,天然聚合物和杂化聚合物。此外,还对静电纺丝SBVs的生物力学性能和生物活性进行了讨论,包括抗血栓形成能力和细胞反应。聚合物共混物似乎是制造SDBV的战略方法,因为它结合了来自合成聚合物的合适的生物力学性质和来自天然聚合物的细胞附着的有利位点。
Small-diameter blood vessels (SDBVs) are still a challenging task to prepare due to the occurrence of thrombosis formation, intimal hyperplasia, and aneurysmal dilation. Electrospinning technique, as a promising tissue engineering approach, can fabricate polymer fibrous scaffolds that satisfy requirements on the construction of extracellular matrix (ECM) of native blood vessel and promote the adhesion, proliferation, and growth of cells. In this review, we summarize the polymers that are deployed for the fabrication of SDBVs and classify them into three categories, synthetic polymers, natural polymers, and hybrid polymers. Furthermore, the biomechanical properties and the biological activities of the electrospun SBVs including anti-thrombogenic ability and cell response are discussed. Polymer blends seem to be a strategic way to fabricate SDBVs because it combines both suitable biomechanical properties coming from synthetic polymers and favorable sites to cell attachment coming from natural polymers.
DOI: 10.1016/j.biomaterials.2009.01.013
发表时间: 2009-05
期刊: BIOMATERIALS
影响因子: 14
作者:
Hong, Yi;Ye, Sang-Ho;Nieponice, Alejandro;Soletti, Lorenzo;Vorp, David A.;Wagner, William R.
通讯作者: Wagner, William R.
用于血管组织工程的电纺明胶/PCL 和胶原/PLCL 支架
DOI: 10.2147/ijn.s61375
发表时间: 2014
影响因子: 8
作者:
Fu W;Liu Z;Feng B;Hu R;He X;Wang H;Yin M;Huang H;Zhang H;Wang W
通讯作者: Wang W
DOI: 10.1126/scitranslmed.3001426
发表时间: 2011-02-02
影响因子: 17.1
作者:
Dahl, Shannon L. M.;Kypson, Alan P.;Niklason, Laura E.
通讯作者: Niklason, Laura E.
DOI: 10.1007/s11706-009-0067-3
发表时间: 2009-12-01
影响因子: 2.7
作者:
Chen, Rui;Morsi, Yosry;Mo, Xiu-mei
通讯作者: Mo, Xiu-mei
DOI: 10.1002/term.136
发表时间: 2009-02-01
影响因子: 3.3
作者:
Hadjipanayi, E.;Mudera, V.;Brown, R. A.
通讯作者: Brown, R. A.