REBASE--a database for DNA restriction and modification: enzymes, genes and genomes.

REBASE--a database for DNA restriction and modification: enzymes, genes and genomes.
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DOI:
10.1093/nar/gkp874
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发表时间:
2010-01
影响因子:
14.9
通讯作者:
Macelis D
Macelis D
中科院分区:
生物学2区
文献类型:
--
作者:
Roberts RJ;Vincze T;Posfai J;Macelis D

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REBASE是一个关于限制性内切酶、DNA甲基转移酶和参与限制性内切修饰(R-M)生物学过程的相关蛋白的综合性数据库。它包含有关识别和裂解位点、同分异构体、新分异构体、商业可用性、甲基化敏感性、晶体和序列数据的完整参考信息。实验表征归巢内切酶也包括在内。REBASE中增长最快的部分包含在序列数据库中发现的假定的R-M系统。所有全测序基因组的R-M内容的全面描述包括概要示意图。REBASE的内容可以通过web (http://rebase.neb.com)浏览,选定的编译可以通过ftp (ftp.neb.com)下载。此外,每月更新可以通过电子邮件请求。
REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in the biological process of restriction–modification (R–M). It contains fully referenced information about recognition and cleavage sites, isoschizomers, neoschizomers, commercial availability, methylation sensitivity, crystal and sequence data. Experimentally characterized homing endonucleases are also included. The fastest growing segment of REBASE contains the putative R–M systems found in the sequence databases. Comprehensive descriptions of the R–M content of all fully sequenced genomes are available including summary schematics. The contents of REBASE may be browsed from the web (http://rebase.neb.com) and selected compilations can be downloaded by ftp (ftp.neb.com). Additionally, monthly updates can be requested via email.
DOI: 10.1126/science.1093857
发表时间: 2004-04-02
期刊: SCIENCE
影响因子: 56.9
作者:
Venter, JC;Remington, K;Smith, HO
通讯作者: Smith, HO
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