The role of birth cohorts in studies of adult health: the New York women's birth cohort.
The role of birth cohorts in studies of adult health: the New York women's birth cohort.
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DOI：
10.1111/j.1365-3016.2009.01061.x
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发表时间：
2009-09
影响因子：
2.8
通讯作者：
Susser E
中科院分区：
文献类型：
--
作者：
Terry MB;Flom J;Tehranifar P;Susser E
调查早期生活因素与成人健康之间关系的流行病学研究往往限于研究成年后可以可靠回忆或从现有医疗记录中获得的暴露。很少有美国研究提供关于产前和产后环境的详细数据，其研究人群现在处于成年期;一个例外是围产期合作项目（CPP）。我们联系了出生于1959年至1963年的CPP纽约站点的前女性参与者，并前瞻性地随访了7年，以检查产前和产后环境是否与出生后40年的女性成年健康相关。纽约CPP队列特别多样化;入组时，母亲的种族/族裔分布约为30%白色、40%黑人和30%波多黎各人。在841名符合条件的女性中，我们成功追踪了375名女性（45%），并招募了262名女性（占追踪人数的70%）。所有符合条件的妇女都有基线数据，我们比较了那些参与其余队列的妇女（n = 579）。7岁时较高的家庭社会经济地位、母亲社会保障号码的可用性和白色种族/族裔在统计学上与较高的追踪概率显著相关。在追踪的受试者中，人种/种族与参与相关，黑人和波多黎各人参与的可能性低于白人（分别为OR = 0.5，95% CI 0.3，0.8和OR = 0.5，95% CI 0.3，1.0）。此外，7年时体重较高与参与率较低相关（OR = 0.95，95% CI 0.92，0.99），但仅在非白人参与者中观察到这种相关性。无论是总体还是每个种族/民族亚组内，其他母体特征、婴儿或幼儿生长指标均与参与或追踪无关。女儿对早期生活因素的回忆，如先兆子痫（敏感性= 24%）和出生体重普遍较差，后者因出生体重而异，最大婴儿的敏感性最高（81%），最小婴儿的敏感性最低（54%）。这些数据加强了需要振兴现有的出生队列与前瞻性数据的生命过程研究的成人健康。了解与追踪和参与这些现有队列相关的因素将有助于解释这些宝贵队列结果的有效性和普遍性。
Epidemiological studies investigating associations between early life factors and adult health are often limited to studying exposures that can be reliably recalled in adulthood or obtained from existing medical records. There are few US studies with detailed data on the pre- and postnatal environment whose study populations are now in adulthood; one exception is the Collaborative Perinatal Project (CPP). We contacted former female participants of the New York site of the CPP who were born from 1959 to 1963 and were prospectively followed for 7 years to examine whether the pre- and postnatal environment is associated with adult health in women 40 years after birth. The New York CPP cohort is particularly diverse; at enrolment, the race/ethnicity distribution of mothers was approximately 30% White, 40% Black and 30% Puerto Rican. Of the 841 eligible women, we successfully traced 375 women (45%) and enrolled 262 women (70% of those traced). Baseline data were available for all eligible women, and we compared those who participated with the remaining cohort (n = 579). Higher family socio-economic status at age 7, availability of maternal social security number, and White race/ethnicity were statistically significantly associated with a higher probability of tracing. Of those traced, race/ethnicity was associated with participation, with Blacks and Puerto Ricans less likely to participate than Whites (OR = 0.5, 95% CI 0.3, 0.8, and OR = 0.5, 95% CI 0.3, 1.0, respectively). In addition, higher weight at 7 years was associated with lower participation (OR = 0.95, 95% CI 0.92, 0.99), but this association was observed only among the non-White participants. None of the other maternal characteristics, infant or early childhood growth measures was associated with participation or with tracing, either overall or within each racial/ ethnic subgroup. Daughters’ recall of early life factors such as pre-eclampsia (sensitivity = 24%) and birthweight were generally poor, with the latter varying by category of birthweight with the highest sensitivity for the largest babies (81%) and the lowest sensitivity for the smallest babies (54%). These data reinforce the need to rejuvenate existing birth cohorts with prospective data for life course studies of adult health. Understanding the factors that are associated with tracing and participation in these existing cohorts will help in interpreting the validity and generalisability of the findings from these invaluable cohorts.
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影响因子：
4.1
作者：
Deary IJ;Gow AJ;Taylor MD;Corley J;Brett C;Wilson V;Campbell H;Whalley LJ;Visscher PM;Porteous DJ;Starr JM
通讯作者：
Starr JM
影响因子：
158.5
作者：
Barker, DJP;Osmond, C;Eriksson, JG
通讯作者：
Eriksson, JG
DOI：
10.1080/07315724.2004.10719428
发表时间：
2004-12-01
影响因子：
3.5
作者：
Barker, DJP
通讯作者：
Barker, DJP
DOI：
10.1073/pnas.100086897
发表时间：
2000-05-23
影响因子：
11.1
作者：
Goldstein, JR;Morning, AJ
通讯作者：
Morning, AJ
影响因子：
--
作者：
Barker, DJP
通讯作者：
Barker, DJP