Microbial Communities in North American Ixodid Ticks of Veterinary and Medical Importance.
Microbial Communities in North American Ixodid Ticks of Veterinary and Medical Importance.
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DOI：
10.3389/fvets.2017.00179
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发表时间：
2017
影响因子：
3.2
通讯作者：
Ricke SC
中科院分区：
文献类型：
--
作者：
Varela-Stokes AS;Park SH;Kim SA;Ricke SC
对吸血节肢动物如蜱（寄生目，硬蜱亚目）的微生物群落或微生物群的兴趣正在增加。对蜱微生物的研究历来强调具有高度医学或兽医重要性的病原体。目前的技术允许同时检测感兴趣的病原体、非致病性共生体，如Coxiella-LE和Francisella-LE，以及未知致病潜力的微生物。虽然每一代蜱虫都是从母体获得的微生物库开始的，但脊椎动物宿主的微栖息地可以改变生命周期中的微生物群。此外，血液喂养可能允许各种致病微生物群的水平交换，这些微生物群可能也可能不能够垂直传播。因此，蜱虫微生物群可能处于不断的变化中。蜱病媒介种群的地理传播使人们对蜱传疾病和与蜱有关的微生物有了更广泛的认识。在过去的十年中，针对16S rRNA基因的下一代测序技术导致了实验室和现场收集的蜱虫生命阶段、不同进食状态的蜱虫和蜱虫组织中细菌群落的记录快照。在种群和个体组织水平上表征蜱虫细菌群落可能导致病原体维持标记的鉴定，从而成为疾病“潜在”而不是疾病状态的指标。确定蜱内微生物群的作用可能导致针对蜱-细菌相互作用的新控制措施。在这里，我们回顾了我们目前对北美硬蜱科（硬蜱）一些媒介微生物群落的了解，并为兽医和医学领域的读者解释了已发表的研究结果，以了解蜱传疾病。
Interest in microbial communities, or microbiota, of blood-feeding arthropods such as ticks (order Parasitiformes, suborder Ixodida) is increasing. Studies on tick microorganisms historically emphasized pathogens of high medical or veterinary importance. Current techniques allow for simultaneous detection of pathogens of interest, non-pathogenic symbionts, like Coxiella-LE and Francisella-LE, and microorganisms of unknown pathogenic potential. While each generation of ticks begins with a maternally acquired repertoire of microorganisms, microhabitats off and on vertebrate hosts can alter the microbiome during the life cycle. Further, blood-feeding may allow for horizontal exchange of various pathogenic microbiota that may or may not also be capable of vertical transmission. Thus, the tick microbiome may be in constant flux. The geographical spread of tick vector populations has resulted in a broader appreciation of tick-borne diseases and tick-associated microorganisms. Over the last decade, next-generation sequencing technology targeting the 16S rRNA gene led to documented snapshots of bacterial communities among life stages of laboratory and field-collected ticks, ticks in various feeding states, and tick tissues. Characterizing tick bacterial communities at population and individual tissue levels may lead to identification of markers for pathogen maintenance, and thus, indicators of disease “potential” rather than disease state. Defining the role of microbiota within the tick may lead to novel control measures targeting tick-bacterial interactions. Here, we review our current understanding of microbial communities for some vectors in the family Ixodidae (hard ticks) in North America, and interpret published findings for audiences in veterinary and medical fields with an appreciation of tick-borne disease.
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影响因子：
5.7
作者：
Hajdušek O;Síma R;Ayllón N;Jalovecká M;Perner J;de la Fuente J;Kopáček P
通讯作者：
Kopáček P
影响因子：
2.1
作者：
Heise, Stephanie R.;Elshahed, M. S.;Little, S. E.
通讯作者：
Little, S. E.
影响因子：
3.7
作者：
Adamson, Steven W.;Browning, Rebecca E.;Karim, Shahid
通讯作者：
Karim, Shahid
影响因子：
3.7
作者：
Trout Fryxell RT;DeBruyn JM
通讯作者：
DeBruyn JM
影响因子：
3.2
作者：
Clayton KA;Gall CA;Mason KL;Scoles GA;Brayton KA
通讯作者：
Brayton KA