Association of single nucleotide polymorphism of chicken uncoupling protein gene with muscle and fatness traits.
Association of single nucleotide polymorphism of chicken uncoupling protein gene with muscle and fatness traits.
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鸡解偶联蛋白基因单核苷酸多态性与肌肉和脂肪性状的关联。
DOI：
10.1111/j.1439-0388.2007.00654.x
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发表时间：
2007-08
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
解偶联蛋白 (UCP) 位于线粒体内膜中，属于转运蛋白家族。 UCP的生物学功能是调节呼吸链产生的质子梯度的释放。结果，ATP 的产生减少，并产生耗散热。本研究旨在探讨UCP基因与鸡生长和身体成分性状的关联。将根据腹部脂肪不同选择的第九代肉鸡品系用作研究群体。 UCP基因的引物是根据鸡基因组序列设计的。采用聚合酶链式反应和限制性片段多态性(PCR-RFLP)方法检测UCP基因外显子3(T1316C)的单核苷酸多态性。 UCP 多态性与肌肉和脂肪特征相关，例如胸小肌重量和腹部脂肪重量。结果表明，UCP基因可能是影响鸡肌肉和脂肪性状的候选基因座或与影响鸡的肌肉和脂肪性状的主基因相关。
Uncoupling proteins (UCPs) are in the mitochondrial inner membrane and belong to the transporter family. The biological function of UCPs is regulating discharge of proton gradient generated by the respiratory chain. As a result, the production of ATP is diminished, and dissipative heat is yielded. The present study was designed to investigate the association of UCP gene with chicken growth and body composition traits. The ninth generation of the broiler lines divergently selected for abdominal fat was used as a research population. Primers for UCP gene were designed from chicken genomic sequence. A single-nucleotide polymorphism, in the exon3 (T1316C) of UCP gene was detected by the polymerase chain reaction and restriction fragment polymorphism (PCR-RFLP) method. The UCP polymorphism was associated with muscle and fatness traits, such as pectoralis minor weight and abdominal fat weight. The results indicated that UCP gene could be a candidate locus or linked to a major gene which affects muscle and fatness traits in chicken.
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影响因子：
30.8
作者：
Fleury, C;Neverova, M;Warden, CH
通讯作者：
Warden, CH
DOI：
10.1016/s1095-6433(02)00113-7
发表时间：
2002-10-01
影响因子：
2.3
作者：
Evock-Clover, CM;Poch, SM;McMurtry, JP
通讯作者：
McMurtry, JP
DOI：
10.5713/ajas.2005.1552
发表时间：
2005-12
期刊：
Asian-australasian Journal of Animal Sciences
影响因子：
--
作者：
Jianguo Zhao;H. Li;Yu-xiang Wang;H. Meng
通讯作者：
Jianguo Zhao;H. Li;Yu-xiang Wang;H. Meng
影响因子：
4.8
作者：
Hamann, A;Flier, JS;Lowell, BB
通讯作者：
Lowell, BB
DOI：
10.5713/ajas.2006.1065
发表时间：
2006-05
期刊：
Asian-australasian Journal of Animal Sciences
影响因子：
--
作者：
J. Oh;H. Kong;Jun-Heon Lee;I. Choi;S. J. Lee;Sang-Goo Lee;B. Sang;C. Choi;B. Cho;G. Jeon;Hye-Ja Lee
通讯作者：
J. Oh;H. Kong;Jun-Heon Lee;I. Choi;S. J. Lee;Sang-Goo Lee;B. Sang;C. Choi;B. Cho;G. Jeon;Hye-Ja Lee