The Iowa Gambling Task in fMRI images.

The Iowa Gambling Task in fMRI images.
复制标题

DOI:
10.1002/hbm.20875
复制
发表时间:
2010-03
影响因子:
4.8
通讯作者:
Bechara, Antoine
Bechara, Antoine
中科院分区:
医学2区
文献类型:
--
作者:
Li, Xiangrui;Lu, Zhong-Lin;D'Argembeau, Arnaud;Ng, Marie;Bechara, Antoine

文献摘要

参考文献

被引文献

相似文献

爱荷华州赌博任务 (IGT) 是一项敏感测试,用于检测多个神经和精​​神病人群的决策障碍。很少有研究在功能磁共振成像研究中使用 IGT,部分原因是这项任务在认知上很复杂。在这里,我们报告了一种在 IGT 执行期间使用功能磁共振成像探索大脑活动的方法。 IGT 期间的决策与一组健康个体的几个大脑区域的活动有关。激活的区域与假设为体细胞标记激活和决策基础的神经回路一致。具体来说,涉及背外侧前额叶皮层(用于工作记忆)、岛叶和后扣带皮层(用于表示情绪状态)、内侧眶额叶和腹内侧前额叶皮层(用于耦合前两个过程)、腹侧纹状体和前扣带回/SMA(补充运动区)的神经回路用于执行行为决策。这些结果对于使用 IGT 研究各种临床人群的异常决策机制具有重要意义。
The Iowa Gambling Task (IGT) is a sensitive test for the detection of decision-making impairments in several neurologic and psychiatric populations. Very few studies have employed the IGT in fMRI investigations, in part, because the task is cognitively complex. Here we report a method for exploring brain activity using fMRI during performance of the IGT. Decision-making during the IGT was associated with activity in several brain regions in a group of healthy individuals. The activated regions were consistent with the neural circuitry hypothesized to underlie somatic marker activation and decision-making. Specifically, a neural circuitry involving the dorsolateral prefrontal cortex (for working memory), the insula and posterior cingulate cortex (for representations of emotional states), the mesial orbitofrontal and ventromedial prefrontal cortex (for coupling the two previous processes), the ventral striatum and anterior cingulate/SMA (supplementary motor area) for implementing behavioral decisions was engaged. These results have implications for using the IGT to study abnormal mechanisms of decision making in a variety of clinical populations.
DOI: 10.1176/appi.ajp.161.10.1913
发表时间: 2004-10-01
影响因子: 17.7
作者:
Dalgleish, T;Yiend, J;Howard, R
通讯作者: Howard, R
DOI: 10.1016/j.geb.2004.06.010
发表时间: 2005-08-01
影响因子: 1.1
作者:
Bechara, A;Damasio, AR
通讯作者: Damasio, AR
DOI: 10.1016/s1053-8119(03)00113-7
发表时间: 2003-07-01
期刊: NEUROIMAGE
影响因子: 5.7
作者:
Bolla, KI;Eldreth, DA;Ernst, M
通讯作者: Ernst, M
DOI: 10.1038/79871
发表时间: 2000-10-01
影响因子: 25
作者:
Damasio, AR;Grabowski, TJ;Hichwa, RD
通讯作者: Hichwa, RD
DOI: 10.1098/rstb.1996.0125
发表时间: 1996-10-29
影响因子: 6.3
作者:
Damasio, AR
通讯作者: Damasio, AR