The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting.
The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting.
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DOI:
10.1146/annurev-immunol-020711-074950
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发表时间:
2013
影响因子:
29.7
通讯作者:
Mortha A
中科院分区:
文献类型:
--
作者:
Merad M;Sathe P;Helft J;Miller J;Mortha A
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes, establishing the DC system as a unique hematopoietic branch. Recent work has also established that tissue DCs consist of developmentally and functionally distinct subsets that differentially regulate T lymphocyte function. This review discusses major advances in our understanding of the regulation of DC lineage commitment, differentiation, diversification, and function in situ.
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DOI:
10.4049/jimmunol.1001802
发表时间:
2010-10-15
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Bobr A;Olvera-Gomez I;Igyarto BZ;Haley KM;Hogquist KA;Kaplan DH
通讯作者:
Kaplan DH
影响因子:
64.8
作者:
ARDAVIN, C;WU, L;SHORTMAN, K
通讯作者:
SHORTMAN, K
影响因子:
30.5
作者:
Bedoui, Sammy;Whitney, Paul G.;Heath, William R.
通讯作者:
Heath, William R.
影响因子:
4.4
作者:
Beaty, Steven R.;Rose, C. Edward, Jr.;Sung, Sun-Sang J.
通讯作者:
Sung, Sun-Sang J.
影响因子:
4.4
作者:
Brawand, P;Fitzpatrick, DR;De Smedt, T
通讯作者:
De Smedt, T