The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting.

The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting.
复制标题

DOI:
10.1146/annurev-immunol-020711-074950
复制
发表时间:
2013
影响因子:
29.7
通讯作者:
Mortha A
Mortha A
中科院分区:
医学1区
文献类型:
--
作者:
Merad M;Sathe P;Helft J;Miller J;Mortha A

文献摘要

参考文献

被引文献

相似文献

树突状细胞(Dendritic cells,DC)形成了一个显著的细胞网络,根据外周线索形成适应性免疫反应。经过40年的研究,我们现在知道DC来自于不同于其他白细胞的造血谱系,确立了DC系统作为独特的造血分支。最近的工作也建立了组织DCs包括发育和功能不同的子集,差异调节T淋巴细胞功能。这篇综述讨论了我们对DC谱系定型、分化、多样化和原位功能调控的理解的主要进展。
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes, establishing the DC system as a unique hematopoietic branch. Recent work has also established that tissue DCs consist of developmentally and functionally distinct subsets that differentially regulate T lymphocyte function. This review discusses major advances in our understanding of the regulation of DC lineage commitment, differentiation, diversification, and function in situ.
DOI: 10.4049/jimmunol.1001802
发表时间: 2010-10-15
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Bobr A;Olvera-Gomez I;Igyarto BZ;Haley KM;Hogquist KA;Kaplan DH
通讯作者: Kaplan DH
DOI: 10.1038/362761a0
发表时间: 1993-04-22
期刊: NATURE
影响因子: 64.8
作者:
ARDAVIN, C;WU, L;SHORTMAN, K
通讯作者: SHORTMAN, K
DOI: 10.1038/ni.1724
发表时间: 2009-05-01
期刊: NATURE IMMUNOLOGY
影响因子: 30.5
作者:
Bedoui, Sammy;Whitney, Paul G.;Heath, William R.
通讯作者: Heath, William R.
DOI: 10.4049/jimmunol.178.3.1882
发表时间: 2007-02-01
影响因子: 4.4
作者:
Beaty, Steven R.;Rose, C. Edward, Jr.;Sung, Sun-Sang J.
通讯作者: Sung, Sun-Sang J.
DOI: 10.4049/jimmunol.169.12.6711
发表时间: 2002-12-15
影响因子: 4.4
作者:
Brawand, P;Fitzpatrick, DR;De Smedt, T
通讯作者: De Smedt, T