Habitat variability correlates with duplicate content of Drosophila genomes.

Habitat variability correlates with duplicate content of Drosophila genomes.
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DOI:
10.1093/molbev/mss133
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发表时间:
2012-10
影响因子:
10.7
通讯作者:
Kawata M
Kawata M
中科院分区:
生物学1区
文献类型:
--
作者:
Makino T;Kawata M

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限制物种栖息地范围的因素对于了解其生物多样性和对环境变化的反应至关重要。然而,产生遗传变异以实现环境适应的遗传和基因组架构仍然知之甚少。在这里,我们表明,重复基因(PD)在全基因组的完全测序果蝇物种的比例显着相关的气候信封和栖息地多样性测量的栖息地内的环境变化。此外,具有低PD的物种由于其更快的进化而倾向于丢失重复的基因。这些结果表明,复制基因的功能限制的快速放松导致低PD的物种具有较低的栖息地多样性,并建议重复基因的维护生物体的生态优势在进化过程中。因此,我们提出,在基因组中的PD与适应环境变化。
The factors limiting the habitat range of species are crucial in understanding their biodiversity and response to environmental change. Yet the genetic and genomic architectures that produce genetic variation to enable environmental adaptation have remained poorly understood. Here we show that the proportion of duplicated genes (PD) in the whole genomes of fully sequenced Drosophila species is significantly correlated with environmental variability within the habitats measured by the climatic envelope and habitat diversity. Furthermore, species with a low PD tend to lose the duplicated genes owing to their faster evolution. These results indicate that the rapid relaxation of functional constraints on duplicated genes resulted in a low PD for species with lower habitat diversity, and suggest that the maintenance of duplicated genes gives organisms an ecological advantage during evolution. We therefore propose that the PD in a genome is related to adaptation to environmental variation.
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