Phytophthora functional genomics database (PFGD): functional genomics of phytophthora-plant interactions.

Phytophthora functional genomics database (PFGD): functional genomics of phytophthora-plant interactions.
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DOI:
10.1093/nar/gkj119
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发表时间:
2006-01-01
影响因子:
14.9
通讯作者:
Kamoun S
Kamoun S
中科院分区:
生物学2区
文献类型:
--
作者:
Gajendran K;Gonzales MD;Farmer A;Archuleta E;Win J;Waugh ME;Kamoun S

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疫霉属功能基因组数据库(PFGD;)由国家基因组资源中心与俄亥俄州大学-俄亥俄州农业研究与发展中心(OSU-OARDC)合作开发,是疫霉属-植物相互作用研究的公开可访问的信息资源。PFGD包含引起马铃薯晚疫病的致病疫霉和影响大豆的大豆疫霉的转录本、基因组、基因表达和功能测定数据。对所有序列数据进行自动化分析,包括源自成簇和组装的表达序列标签的共有序列。PFGD搜索过滤器界面允许使用修饰符、注释关键字或序列名称直观地导航按文库和衍生查询组织的转录本和基因组数据。为从转录物和基因组序列构建的文库提供BLAST服务。转录数据可视化工具包括质量筛选、多序列比对以及特征和注释查看器。还提供了一种通过新的动态功能注释比较来支持比较分析的基因组浏览器。PFGD与茄科基因组学数据库(SolGD;)集成,以帮助深入了解感染和抗性机制,特别是与疫霉属病原体及其植物宿主相关的机制。
The Phytophthora Functional Genomics Database (PFGD; ), developed by the National Center for Genome Resources in collaboration with The Ohio State University-Ohio Agricultural Research and Development Center (OSU-OARDC), is a publicly accessible information resource for Phytophthora–plant interaction research. PFGD contains transcript, genomic, gene expression and functional assay data for Phytophthora infestans, which causes late blight of potato, and Phytophthora sojae, which affects soybeans. Automated analyses are performed on all sequence data, including consensus sequences derived from clustered and assembled expressed sequence tags. The PFGD search filter interface allows intuitive navigation of transcript and genomic data organized by library and derived queries using modifiers, annotation keywords or sequence names. BLAST services are provided for libraries built from the transcript and genomic sequences. Transcript data visualization tools include Quality Screening, Multiple Sequence Alignment and Features and Annotations viewers. A genomic browser that supports comparative analysis via novel dynamic functional annotation comparisons is also provided. PFGD is integrated with the Solanaceae Genomics Database (SolGD; ) to help provide insight into the mechanisms of infection and resistance, specifically as they relate to the genus Phytophthora pathogens and their plant hosts.
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