Overall and cause-specific mortality rates among men and women with high exposure to indoor air pollution from the use of smoky and smokeless coal: a cohort study in Xuanwei, China.
Overall and cause-specific mortality rates among men and women with high exposure to indoor air pollution from the use of smoky and smokeless coal: a cohort study in Xuanwei, China.
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DOI：
10.1136/bmjopen-2021-058714
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发表时间：
2022-11-15
期刊：
影响因子：
2.9
通讯作者：
Lan, Qing
中科院分区：
文献类型：
--
作者：
Nagaradona, Teja;Bassig, Bryan A.;Hosgood, Dean;Vermeulen, Roel C. H.;Ning, Bofu;Seow, Wei Jie;Hu, Wei;Portengen, Luetzen;Wong, Jason;Shu, Xiao-Ou;Zheng, Wei;Appel, Nathan;Gao, Yu-Tang;Cai, Qiu-Yin;Yang, Gong;Chen, Ying;Downward, George;Li, Jihua;Yang, Kaiyun;McCullough, Lauren;Silverman, Debra;Huang, Yunchao;Lan, Qing
中国宣威（XW）从不吸烟的女性肺癌发病率是全国最高的。这是由于燃烧用于室内烹饪和取暖的无烟煤。本研究的目的是评估这一独特人群的死因特异性死亡率谱，包括使用无烟煤的人群，无烟煤被认为是XW的“清洁”煤，因为这还没有得到很好的表征。队列研究。XW是中国的一个农村地区，那里的居民经常燃烧煤炭来进行室内烹饪和取暖。计算并比较了1976年至2011年期间XW的42420名男性和女性中终身吸烟和无烟煤炭使用者的经性别调整的特定原因死亡率。将XW妇女的死亡率与上海一组绝大多数从不吸烟的妇女的死亡率进行比较。煤烟用户的死亡率是由癌症（41%）驱动的，肺癌占癌症死亡的88%。相比之下，心血管疾病（CVD）占无烟煤使用者死亡人数的32%，其中7%死于癌症。与无烟煤使用者相比，无烟煤使用者的癌症总死亡率高出四倍，特别是肺癌（标准化比率（SRR）=17.6）。无烟煤使用者CVD（SRR=2.9）和肺炎（SRR=2.5）的死亡率高于煤烟使用者。这些模式在男性和女性中是相似的，尽管XW女性很少吸烟。无论使用何种煤种，XW的女性总体死亡率都比上海女性高出三倍以上，并且大多数特定原因的结局都高于上海女性。基于不同煤种的终生使用，XW的死因别死亡率负担不同。这些观察结果证明，消除室内烹饪和取暖的所有煤炭使用是改善公共卫生的重要下一步，特别是在发展中国家。
Never-smoking women in Xuanwei (XW), China, have some of the highest lung cancer rates in the country. This has been attributed to the combustion of smoky coal used for indoor cooking and heating. The aim of this study was to evaluate the spectrum of cause-specific mortality in this unique population, including among those who use smokeless coal, considered ‘cleaner’ coal in XW, as this has not been well-characterised. Cohort study. XW, a rural region of China where residents routinely burn coal for indoor cooking and heating. Age-adjusted, cause-specific mortality rates between 1976 and 2011 were calculated and compared among lifetime smoky and smokeless coal users in a cohort of 42 420 men and women from XW. Mortality rates for XW women were compared with those for a cohort of predominately never-smoking women in Shanghai. Mortality in smoky coal users was driven by cancer (41%), with lung cancer accounting for 88% of cancer deaths. In contrast, cardiovascular disease (CVD) accounted for 32% of deaths among smokeless coal users, with 7% of deaths from cancer. Total cancer mortality was four times higher among smoky coal users relative to smokeless coal users, particularly for lung cancer (standardised rate ratio (SRR)=17.6). Smokeless coal users had higher mortality rates of CVD (SRR=2.9) and pneumonia (SRR=2.5) compared with smoky coal users. These patterns were similar in men and women, even though XW women rarely smoked cigarettes. Women in XW, regardless of coal type used, had over a threefold higher rate of overall mortality, and most cause-specific outcomes were elevated compared with women in Shanghai. Cause-specific mortality burden differs in XW based on the lifetime use of different coal types. These observations provide evidence that eliminating all coal use for indoor cooking and heating is an important next step in improving public health particularly in developing countries.
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DOI：
10.4103/1947-2714.117290
发表时间：
2013-08
期刊：
North American journal of medical sciences
影响因子：
--
作者：
Uzoigwe JC;Prum T;Bresnahan E;Garelnabi M
通讯作者：
Garelnabi M
影响因子：
10.4
作者：
Bonjour S;Adair-Rohani H;Wolf J;Bruce NG;Mehta S;Prüss-Ustün A;Lahiff M;Rehfuess EA;Mishra V;Smith KR
通讯作者：
Smith KR
影响因子：
10.4
作者：
Shen M;Chapman RS;Vermeulen R;Tian L;Zheng T;Chen BE;Engels EA;He X;Blair A;Lan Q
通讯作者：
Lan Q
影响因子：
6.4
作者：
Wong, Jason Y. Y.;Downward, George S.;Hu, Wei;Portengen, Lutzen;Seow, Wei Jie;Silverman, Debra T.;Bassig, Bryan A.;Zhang, Jinming;Xu, Jun;Ji, Bu-Tian;Li, Jihua;He, Jun;Yang, Kaiyun;Tian, Linwei;Shen, Min;Huang, Yunchao;Vermeulen, Roel;Rothman, Nathaniel;Lan, Qing
通讯作者：
Lan, Qing
影响因子：
10.4
作者：
Vermeulen, Roel;Downward, George S.;Lan, Qing
通讯作者：
Lan, Qing