Interspecies Behavioral Variability of Medaka Fish Assessed by Comparative Phenomics.
Interspecies Behavioral Variability of Medaka Fish Assessed by Comparative Phenomics.
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通过比较现象学评估的medaka鱼的种间行为变异性。
DOI：
10.3390/ijms22115686
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发表时间：
2021-05-26
影响因子：
5.6
通讯作者：
Hsiao CD
中科院分区：
文献类型：
--
作者：
Audira G;Siregar P;Chen KH;Roldan MJM;Huang JC;Lai HT;Hsiao CD
近年来，青鳉已被用作各种研究领域的模式生物。然而，尽管它比斑马鱼具有一些优势，但与斑马鱼相比，青鳉的研究较少，特别是关于其行为的研究。因此，为了提供更多关于其行为的信息，并证明几种青鳉之间的行为差异，我们比较了四种青鳉鱼，青鳉，Oryzias dancena，Oryzias woworae和Oryzias sinensis之间的行为表现和脑中生物标志物的表达。我们发现，每个青鳉物种明显表现出不同的行为，这可能与不同的基础水平的几个生物标志物。此外，通过表型组学和基于基因组的聚类，这些青鳉鱼之间的差异进行了进一步研究。这里，基于表型的聚类是基于行为结果，而基于基因组的聚类是基于nd2基因的序列。正如我们所料，两个聚类显示出一些相似性，对方之间的种间关系青鳉和斑马鱼。然而，这种相似性并没有显示在青鳉种间比较的两个聚类。因此，这些结果表明，在比较生物学的几个先前的研究重新解释。我们希望这些结果有助于不断增长的数据库的青鳉鱼的表型，并为未来的青鳉鱼的表型组学研究的基础之一。
Recently, medaka has been used as a model organism in various research fields. However, even though it possesses several advantages over zebrafish, fewer studies were done in medaka compared to zebrafish, especially with regard to its behavior. Thus, to provide more information regarding its behavior and to demonstrate the behavioral differences between several species of medaka, we compared the behavioral performance and biomarker expression in the brain between four medaka fishes, Oryzias latipes, Oryzias dancena, Oryzias woworae, and Oryzias sinensis. We found that each medaka species explicitly exhibited different behaviors to each other, which might be related to the different basal levels of several biomarkers. Furthermore, by phenomics and genomic-based clustering, the differences between these medaka fishes were further investigated. Here, the phenomic-based clustering was based on the behavior results, while the genomic-based clustering was based on the sequence of the nd2 gene. As we expected, both clusterings showed some resemblances to each other in terms of the interspecies relationship between medaka and zebrafish. However, this similarity was not displayed by both clusterings in the medaka interspecies comparisons. Therefore, these results suggest a re-interpretation of several prior studies in comparative biology. We hope that these results contribute to the growing database of medaka fish phenotypes and provide one of the foundations for future phenomics studies of medaka fish.
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影响因子：
4.6
作者：
Baker MR;Goodman AC;Santo JB;Wong RY
通讯作者：
Wong RY
DOI：
10.3791/4196
发表时间：
2012-11-18
期刊：
Journal of visualized experiments : JoVE
影响因子：
--
作者：
Avdesh A;Chen M;Martin-Iverson MT;Mondal A;Ong D;Rainey-Smith S;Taddei K;Lardelli M;Groth DM;Verdile G;Martins RN
通讯作者：
Martins RN
DOI：
10.1016/0024-3205(68)90182-3
发表时间：
1968-01-01
期刊：
LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY
影响因子：
--
作者：
APRISON, MH;SHANK, RP;WERMAN, R
通讯作者：
WERMAN, R
影响因子：
2.5
作者：
Adams, DC;Anthony, CD
通讯作者：
Anthony, CD
斑马鱼（Danio Rerio）的焦虑度量：黑色/白色偏好和新型坦克测试的解离。
影响因子：
3.7
作者：
Blaser RE;Rosemberg DB
通讯作者：
Rosemberg DB