Relationships between telocytes and cardiomyocytes during pre- and post-natal life.
Relationships between telocytes and cardiomyocytes during pre- and post-natal life.
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产前和产后生活期间端细胞和心肌细胞之间的关系。
DOI：
10.1111/j.1582-4934.2010.01074.x
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发表时间：
2010-05
影响因子：
5.3
通讯作者：
Bani D
中科院分区：
文献类型：
--
作者：
Faussone-Pellegrini MS;Bani D
已有证据表明，成人心脏含有一个特定的基质细胞群，与心肌细胞和心外膜下心源性壁龛中的心脏干细胞存在密切的空间关系。最近被称为“端细胞”，因为它们的长的细胞质过程包围实质细胞，这些细胞已被假定参与心脏形态发生。在我们看来，调查心脏组织发生过程中端细胞的发生和形态可能会进一步阐明这个问题。我们的研究结果表明，典型的端细胞存在于小鼠心脏的早期胚胎到成年生活。这些细胞以其细长的胞质突起紧密地包围着生长中的心肌细胞。因此，在发育中的心肌，端细胞可能发挥护理和指导作用的心肌前体，以形成正确的三维组织结构模式，如前所述。
Evidence has been given that the adult heart contains a specific population of stromal cells lying in close spatial relationship with cardiomyocytes and with cardiac stem cells in sub-epicardial cardiogenic niches. Recently termed ‘telocytes’ because of their long cytoplasmic processes embracing the parenchymal cells, these cells have been postulated to be involved in heart morphogenesis. In our opinion, investigating the occurrence and morphology of telocytes during heart histogenesis may shed further light on this issue. Our findings show that typical telocytes are present in the mouse heart by early embryonic to adult life. These cells closely embrace the growing cardiomyocytes with their long, slender cytoplasmic processes. Hence, in the developing myocardium, telocytes may play nursing and guiding roles for myocardial precursors to form the correct three-dimensional tissue architectural pattern, as previously suggested.
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影响因子：
--
作者：
Torella, Daniele;Ellison, Georgina M;Nadal-Ginard, Bernardo
通讯作者：
Nadal-Ginard, Bernardo
影响因子：
5.3
作者：
Popescu LM;Gherghiceanu M;Manole CG;Faussone-Pellegrini MS
通讯作者：
Faussone-Pellegrini MS
影响因子：
5.3
作者：
Kostin S;Popescu LM
通讯作者：
Popescu LM
DOI：
10.1073/pnas.0706760104
发表时间：
2007-08-28
影响因子：
11.1
作者：
Bearzi, Claudia;Rota, Marcello;Anversa, Piero
通讯作者：
Anversa, Piero
影响因子：
1
作者：
Doljanski, F
通讯作者：
Doljanski, F