Neuroendocrine targets of endocrine disruptors.
Neuroendocrine targets of endocrine disruptors.
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DOI：
10.14310/horm.2002.1249
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发表时间：
2010-01
期刊：
影响因子：
--
通讯作者：
Gore AC
中科院分区：
文献类型：
--
作者：
Gore AC
中枢神经内分泌系统负责控制体内的稳态过程，包括生殖、生长、代谢和能量平衡以及应激反应。这些过程是由中枢神经系统（特别是下丘脑）中的信号启动的，首先由神经效应器传递，然后由内分泌效应器传递。神经内分泌系统作为连接大脑和外周内分泌系统的纽带，在正常情况下对生物体对环境的反应能力起着至关重要的作用。当神经内分泌稳态被环境内分泌干扰化学品破坏时，各种扰动可能随之而来，特别是当内分泌干扰发生在关键发育时期时。本文将讨论环境内分泌干扰神经内分泌系统的证据，以及对内分泌和生殖功能的后遗症。
The central neuroendocrine systems are responsible for the control of homeostatic processes in the body, including reproduction, growth, metabolism and energy balance, and stress responsiveness. These processes are initiated by signals in the central nervous system, specifically the hypothalamus, and are conveyed first by neural and then by endocrine effectors. The neuroendocrine systems, as the links between the brain and peripheral endocrine systems, play critical roles in the ability of an organism to respond to its environment under normal circumstances. When neuroendocrine homeostasis is disrupted by environmental endocrine-disrupting chemicals, a variety of perturbations can ensue, particularly when endocrine disruption occurs during critical developmental time periods. This article will discuss the evidence for environmental endocrine disruption of neuroendocrine systems, and the sequelae on endocrine and reproductive functions.
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DOI：
10.1073/pnas.0610410104
发表时间：
2007-04-03
影响因子：
11.1
作者：
Crews, David;Gore, Andrea C.;Skinner, Michael K.
通讯作者：
Skinner, Michael K.
影响因子：
3.6
作者：
Bisenius, Erin S.;Veeramachaneni, D. N. Rao;Tobet, Stuart
通讯作者：
Tobet, Stuart
影响因子：
8.2
作者：
Dickerson, Sarah M.;Gore, Andrea C.
通讯作者：
Gore, Andrea C.
影响因子：
4.8
作者：
Anway, Matthew D.;Leathers, Charles;Skinner, Michael K.
通讯作者：
Skinner, Michael K.
影响因子：
3.5
作者：
ARAI, Y;MURAKAMI, S;NISHIZUKA, M
通讯作者：
NISHIZUKA, M