Objectively measured physical activity, sedentary behaviour and all-cause mortality in older men: does volume of activity matter more than pattern of accumulation?
Objectively measured physical activity, sedentary behaviour and all-cause mortality in older men: does volume of activity matter more than pattern of accumulation?
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DOI：
10.1136/bjsports-2017-098733
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发表时间：
2019-08
影响因子：
18.4
通讯作者：
Whincup PH
中科院分区：
文献类型：
--
作者：
Jefferis BJ;Parsons TJ;Sartini C;Ash S;Lennon LT;Papacosta O;Morris RW;Wannamethee SG;Lee IM;Whincup PH
了解设备测量的久坐行为和身体活动与老年男性的全因死亡率之间的关系，老年男性是一个高度不活动和久坐行为的年龄组。1978-1980年间从英国24家全科医院招募的男性进行前瞻性人群队列研究。2010-2012年，3137名幸存的男性被邀请进行随访，1655名（71-92岁）同意。护士测量身高和体重，男性完成健康和人口调查问卷，并佩戴ActiGraph GT3x加速度计。截至2016年6月1日，通过国家卫生服务中心登记收集了全因死亡率。在平均5.0年的随访后，1181名没有心血管疾病的男性中有194人死亡。每增加30分钟的久坐行为或轻度身体活动（LIPA），或10分钟的中度至剧烈身体活动（MVPA），死亡率的hr分别为1.17 （95% CI 1.10至1.25）、0.83 （95% CI 0.77至0.90）和0.90 （95% CI 0.84至0.96）。对混杂因素的调整并没有显著改变估计值。只有LIPA在所有强度的相互调节上保持显著。散发性分钟累积150分钟MVPA/周（66%的男性达到）的HR为0.59 (95% CI 0.43至0.81)，持续≥10分钟的回合累积150分钟MVPA/周（16%的男性达到）的HR为0.58 （95% CI 0.33至1.00）。久坐休息与死亡率无关。在老年男性中，所有活动（轻强度以上）都是有益的，超过总活动量，≥10分钟的活动积累似乎并不重要。研究结果可以为老年人的体育活动指南提供信息。
To understand how device-measured sedentary behaviour and physical activity are related to all-cause mortality in older men, an age group with high levels of inactivity and sedentary behaviour. Prospective population-based cohort study of men recruited from 24 UK General Practices in 1978–1980. In 2010–2012, 3137 surviving men were invited to a follow-up, 1655 (aged 71–92 years) agreed. Nurses measured height and weight, men completed health and demographic questionnaires and wore an ActiGraph GT3x accelerometer. All-cause mortality was collected through National Health Service central registers up to 1 June 2016. After median 5.0 years’ follow-up, 194 deaths occurred in 1181 men without pre-existing cardiovascular disease. For each additional 30 min in sedentary behaviour, or light physical activity (LIPA), or 10 min in moderate to vigorous physical activity (MVPA), HRs for mortality were 1.17 (95% CI 1.10 to 1.25), 0.83 (95% CI 0.77 to 0.90) and 0.90 (95% CI 0.84 to 0.96), respectively. Adjustments for confounders did not meaningfully change estimates. Only LIPA remained significant on mutual adjustment for all intensities. The HR for accumulating 150 min MVPA/week in sporadic minutes (achieved by 66% of men) was 0.59 (95% CI 0.43 to 0.81) and 0.58 (95% CI 0.33 to 1.00) for accumulating 150 min MVPA/week in bouts lasting ≥10 min (achieved by 16% of men). Sedentary breaks were not associated with mortality. In older men, all activities (of light intensity upwards) were beneficial and accumulation of activity in bouts ≥10 min did not appear important beyond total volume of activity. Findings can inform physical activity guidelines for older adults.
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影响因子：
4.1
作者：
Fishman EI;Steeves JA;Zipunnikov V;Koster A;Berrigan D;Harris TA;Murphy R
通讯作者：
Murphy R
影响因子：
16.2
作者：
Dunstan DW;Kingwell BA;Larsen R;Healy GN;Cerin E;Hamilton MT;Shaw JE;Bertovic DA;Zimmet PZ;Salmon J;Owen N
通讯作者：
Owen N
影响因子：
4.5
作者：
Jefferis BJ;Sartini C;Lee IM;Choi M;Amuzu A;Gutierrez C;Casas JP;Ash S;Lennnon LT;Wannamethee SG;Whincup PH
通讯作者：
Whincup PH
DOI：
10.1186/s12966-016-0338-1
发表时间：
2016-02-04
影响因子：
8.7
作者：
Jefferis, Barbara J.;Sartini, Claudio;Whincup, Peter H.
通讯作者：
Whincup, Peter H.
影响因子：
3.7
作者：
Koster A;Caserotti P;Patel KV;Matthews CE;Berrigan D;Van Domelen DR;Brychta RJ;Chen KY;Harris TB
通讯作者：
Harris TB