Psychosocial co-morbidities in Interstitial Cystitis/Bladder Pain syndrome (IC/BPS): A systematic review.

Psychosocial co-morbidities in Interstitial Cystitis/Bladder Pain syndrome (IC/BPS): A systematic review.
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DOI:
10.1002/nau.23421
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发表时间:
2018-03
影响因子:
2
通讯作者:
Williams DA
Williams DA
中科院分区:
医学3区
文献类型:
--
作者:
McKernan LC;Walsh CG;Reynolds WS;Crofford LJ;Dmochowski RR;Williams DA

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心理社会因素会加剧间质性膀胱炎 (IC/BPS) 的症状。虽然社会心理自我管理对其他疼痛状况有效,但其对 IC/BPS 人群的影响却很少被研究。本次综述的目的是了解心理社会因素对 IC/BPS 的普遍性和影响,评估基线心理社会特征,并提供评估和治疗建议。遵循 PRISMA 指南,主要信息来源是 PubMed,包括 MEDLINE、Embase、CINAHL 和 GoogleScholar。纳入标准包括:(i) 明确定义的 IC/BPS 或慢性盆腔疼痛综合征队列,前提是 IC/BPS 队列由主要队列的定量结果描述; (ii) 所有性别和地区; (iii) 1995年至2017年4月14日期间用英文撰写的研究报告; (iv) 作为结果测量或至少作为基线特征的心理社会因素的定量报告。最初的 642 篇文章中的 34 篇经过了审查。定量分析表明 IC/BPS 的心理社会困难程度,在所有指标上均低于平均水平,并且在 10 项指标中,有 7 项属于临床关注的领域。荟萃分析显示,简式 12 健康调查 (MCS) 的平均心理成分得分为 40.80 (SD 6.25,N = 2912),其中 <36 与严重心理障碍一致。各项研究的平均得分在临床抑郁症(CES-D 19.89,SD 13.12,N = 564)和广泛性焦虑症(HADS-A 8.15,SD 4.85,N = 465)中所见的范围内。 IC/BPS 的心理影响是普遍且严重的。缺乏现有的治疗证据,表明自我管理干预可能会有所帮助。
Psychosocial factors amplify symptoms of Interstitial Cystitis (IC/BPS). While psychosocial self-management is efficacious in other pain conditions, its impact on an IC/BPS population has rarely been studied. The objective of this review is to learn the prevalence and impact of psychosocial factors on IC/BPS, assess baseline psychosocial characteristics, and offer recommendations for assessment and treatment. Following PRISMA guidelines, primary information sources were PubMed including MEDLINE, Embase, CINAHL, and GoogleScholar. Inclusion criteria included: (i) a clearly defined cohort with IC/BPS or with Chronic Pelvic Pain Syndrome provided the IC/BPS cohort was delineated with quantitative results from the main cohort; (ii) all genders and regions; (iii) studies written in English from 1995 to April 14, 2017; (iv) quantitative report of psychosocial factors as outcome measures or at minimum as baseline characteristics. Thirty-four of an initial 642 articles were reviewed. Quantitative analyses demonstrate the magnitude of psychosocial difficulties in IC/BPS, which are worse than average on all measures, and fall into areas of clinical concern for 7 out of 10 measures. Meta-analyses shows mean Mental Component Score of the Short-Form 12 Health Survey (MCS) of 40.80 (SD 6.25, N = 2912), where <36 is consistent with severe psychological impairment. Averaged across studies, the population scored in the range seen in clinical depression (CES-D 19.89, SD 13.12, N = 564) and generalized anxiety disorder (HADS-A 8.15, SD 4.85, N = 465). The psychological impact of IC/BPS is pervasive and severe. Existing evidence of treatment is lacking and suggests self-management intervention may be helpful.
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